HitPredict

Interactor 1: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Interactor 2: UBL4B (Q8N7F7)
Ubiquitin-like protein 4B
Gene: UBL4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 316 Hs			1 174
+	Hs
		474952 BRCC3_HUMAN (13-316): 6.26e-139: 397: 100.00		UBB_HUMAN (1-72): 6.02e-33: 118: 30.56
+	Hs
		130837 PSDE_HUMAN (6-309): 7.58e-75: 234: 21.47		RS27A_HUMAN (1-141): 3.76e-46: 150: 21.68
+	Hs
		130716 PSDE_HUMAN (6-309): 7.58e-75: 234: 21.47		UBL4A_HUMAN (1-153): 6.1e-39: 131: 42.41
+	At
		1092172 PSDE_ARATH (6-310): 3.47e-76: 237: 21.73		UBQ3_ARATH (1-77): 1e-31: 117: 27.27
+	Hs
		130704 PSDE_HUMAN (6-309): 7.58e-75: 234: 21.47		UBB_HUMAN (1-72): 6.02e-33: 118: 30.56
+	Hs
		130838 PSDE_HUMAN (6-309): 7.58e-75: 234: 21.47		RL40_HUMAN (1-112): 3.5e-34: 118: 21.43
+	At
		1091793 CSN5A_ARATH (9-214): 8.6e-70: 222: 22.12		UBQ3_ARATH (1-77): 1e-31: 117: 27.27
+	Sc
		477336 RPN11_YEAST (7-267): 4.22e-68: 216: 19.03		UBI4P_YEAST (1-72): 6.29e-11: 61.7: 30.56
+	Sc
		477501 CSN5_YEAST (6-297): 2.13e-49: 172: 15.31		UBI4P_YEAST (1-72): 6.29e-11: 61.7: 30.56