HitPredict

Interactor 1: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Interactor 2: C1QT1 (Q9BXJ1)
Complement C1q tumor necrosis factor-related protein 1 (G protein-coupled receptor-interacting protein) (GIP)
Gene: C1QTNF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Collagen~Collagen
Common GO terms	GO:0005581 - collagen trimer GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1754 Hs			1 281
+	Hs
		810606 COIA1_HUMAN (1-1754): 0: 1034: 99.60		ADIPO_HUMAN (53-280): 2.91e-49: 165: 28.51
+	Hs
		388771 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1QC_HUMAN (39-278): 3.41e-42: 146: 21.25
+	Hs
		810633 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1QT7_HUMAN (44-280): 5.52e-41: 144: 25.00
+	Hs
		810609 COIA1_HUMAN (1-1754): 0: 1034: 99.60		Q4VAQ0_HUMAN (1-277): 1.89e-34: 130: 21.54
+	Hs
		668774 COIA1_HUMAN (1-1754): 0: 1034: 99.60		CO8A2_HUMAN (103-277): 3.65e-33: 129: 27.84
+	Hs
		810618 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1QL4_HUMAN (72-278): 1.02e-32: 121: 27.40
+	Hs
		694312 COIA1_HUMAN (1-1754): 0: 1034: 99.60		CO8A1_HUMAN (117-277): 2.18e-26: 110: 25.93
+	Hs
		505804 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1T9A_HUMAN (77-169): 9.99e-10: 60.3: 21.78
+	Hs
		73781 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1T9B_HUMAN (77-169): 1.1e-09: 60.3: 21.78
+	Hs
		388700 COIA1_HUMAN (1-1754): 0: 1034: 99.60		C1QB_HUMAN (5-64): 1.09e-09: 59.5: 11.67
+	Hs
		384291 CO3A1_HUMAN (594-1487): 2.36e-59: 228: 27.80		C1QT1_HUMAN (1-281): 3.6e-81: 247: 100.00
+	Hs
		471606 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		C1QT1_HUMAN (1-281): 3.6e-81: 247: 100.00
+	Hs
		388761 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		C1QC_HUMAN (39-278): 3.41e-42: 146: 21.25
+	Hs
		471607 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		C1QT2_HUMAN (44-280): 1.85e-37: 135: 21.83
+	Hs
		471593 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		Q4VAQ0_HUMAN (1-277): 1.89e-34: 130: 21.54
+	Hs
		471583 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		CO8A2_HUMAN (103-277): 3.65e-33: 129: 27.84
+	Hs
		471574 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		C1T9A_HUMAN (77-169): 9.99e-10: 60.3: 21.78
+	Hs
		471587 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		COAA1_HUMAN (80-146): 2.06e-09: 60.1: 35.82
+	Hs
		388686 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		C1QB_HUMAN (5-64): 1.09e-09: 59.5: 11.67
+	Hs
		471605 CO4A2_HUMAN (871-1678): 1.04e-54: 213: 21.65		COLA1_HUMAN (2-144): 8.28e-09: 58.3: 14.89