Interactor 1: CO8A2 (P25067)
Collagen alpha-2(VIII) chain (Endothelial collagen)
Gene: COL8A2

Interactor 2: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Collagen~Collagen
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005604 - basement membrane
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 703
Hs

1 1754
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Last updated: 11Aug2025