Protein: HXC8
Homeobox protein Hox-C8 (Homeobox protein Hox-3A)

Gene: HXC8, HOXC8
Organism: Homo sapiens
Interactions: 133
UniProt ID: P31273

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678886

PBX1
Pre-B-cell leukemia transcription factor 1

3

20

Small-scale

0.843

High

241216

TBX19
T-box transcription factor TBX19

2

20

High-throughput

0.783

High

308057

VENTX
Homeobox protein VENTX

2

19

High-throughput

0.783

High

641327

PAX6
Paired box protein Pax-6

2

20

High-throughput

0.783

High

678775

HXD3
Homeobox protein Hox-D3

2

17

High-throughput

0.783

High

678887

PBX2
Pre-B-cell leukemia transcription factor 2

2

20

High-throughput

0.783

High

678889

MEOX1
Homeobox protein MOX-1

2

17

High-throughput

0.783

High

678891

LHX2
LIM/homeobox protein Lhx2

2

14

High-throughput

0.783

High

678898

PO6F2
POU domain, class 6, transcription factor 2

2

20

High-throughput

0.783

High

678970

PBX4
Pre-B-cell leukemia transcription factor 4

2

20

High-throughput

0.783

High

678980

LHX3
LIM/homeobox protein Lhx3

2

15

High-throughput

0.783

High

678981

HESX1
Homeobox expressed in ES cells 1

2

19

High-throughput

0.783

High

678987

TBX22
T-box transcription factor TBX22

2

20

High-throughput

0.783

High

678935

Q6FHY5
MEOX2 protein

1

18

High-throughput

0.665

High

658621

MSX1
Homeobox protein MSX-1

1

19

Small-scale

0.647

High

678892

DLX5
Homeobox protein DLX-5

1

19

Small-scale

0.647

High

678906

DLX2
Homeobox protein DLX-2

1

19

Small-scale

0.647

High

678986

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

9

High-throughput

0.628

High

678890

MEOX2
Homeobox protein MOX-2

1

18

High-throughput

0.621

High

678910

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

3

20

High-throughput

0.607

High

204297

MS18B
Protein Mis18-beta

2

2

High-throughput

0.606

High

252962

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

320663

LDOC1
Protein LDOC1

2

1

High-throughput

0.606

High

536738

TRI27
Zinc finger protein RFP

2

10

High-throughput

0.606

High

678900

PAX5
Paired box protein Pax-5

2

20

High-throughput

0.606

High

678904

PAX8
Paired box protein Pax-8

2

20

High-throughput

0.606

High

678908

TLE5
TLE family member 5

2

20

High-throughput

0.606

High

678915

TRIP6
Thyroid receptor-interacting protein 6

2

5

High-throughput

0.606

High

678931

MYOME
Myomegalin

2

1

High-throughput

0.606

High

678943

TBCD1
TBC1 domain family member 1

2

4

High-throughput

0.606

High

678955

IKBD
NF-kappa-B inhibitor delta

2

20

High-throughput

0.606

High

678956

ZFP90
Zinc finger protein 90 homolog

2

1

High-throughput

0.606

High

678957

TEKT4
Tektin-4

2

4

High-throughput

0.606

High

678961

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

7

High-throughput

0.606

High

678965

TRIB3
Tribbles homolog 3

2

4

High-throughput

0.606

High

678966

PFD5
Prefoldin subunit 5

2

2

High-throughput

0.606

High

678971

PRD14
PR domain zinc finger protein 14

2

12

High-throughput

0.606

High

678972

GO45
Golgin-45

2

1

High-throughput

0.606

High

678975

CFA68
Cilia- and flagella-associated protein 68

2

1

High-throughput

0.606

High

678976

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

12

High-throughput

0.606

High

678977

AIRIM
AFG2-interacting ribosome maturation factor

2

2

High-throughput

0.606

High

678978

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.606

High

678983

ZRAN1
Ubiquitin thioesterase ZRANB1

2

4

High-throughput

0.606

High

678984

IKZF3
Zinc finger protein Aiolos

2

7

High-throughput

0.606

High

409339

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

2

0

High-throughput

0.580

High

678917

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.580

High

678982

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.580

High

206938

SMAD6
Mothers against decapentaplegic homolog 6

1

12

Small-scale

0.573

High

678916

SMAD1
Mothers against decapentaplegic homolog 1

1

12

Small-scale

0.573

High

678962

RBPMS
RNA-binding protein with multiple splicing

1

3

High-throughput

0.560

High

62276

GG6L9
Golgin subfamily A member 6-like protein 9

2

8

High-throughput

0.553

High

66997

CRTP1
Cysteine-rich tail protein 1

2

5

High-throughput

0.553

High

180685

PA2GX
Group 10 secretory phospholipase A2

2

1

High-throughput

0.553

High

280534

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.553

High

280776

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.553

High

533648

GYS1
Glycogen [starch] synthase, muscle

2

2

High-throughput

0.553

High

678893

KR121
Keratin-associated protein 12-1

2

7

High-throughput

0.553

High

678894

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.553

High

678895

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

678896

KR109
Keratin-associated protein 10-9

2

20

High-throughput

0.553

High

678905

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

678909

TRAF1
TNF receptor-associated factor 1

2

9

High-throughput

0.553

High

678920

KRA61
Keratin-associated protein 6-1

2

3

High-throughput

0.553

High

678921

KRA62
Keratin-associated protein 6-2

2

3

High-throughput

0.553

High

678923

KR133
Keratin-associated protein 13-3

2

5

High-throughput

0.553

High

678927

PKHG4
Puratrophin-1

2

2

High-throughput

0.553

High

678929

ARH
Low density lipoprotein receptor adapter protein 1

2

8

High-throughput

0.553

High

678930

KPRP
Keratinocyte proline-rich protein

2

2

High-throughput

0.553

High

678932

TENS2
Tensin-2

2

3

High-throughput

0.553

High

678934

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.553

High

678936

NADE
Glutamine-dependent NAD(+) synthetase

2

1

High-throughput

0.553

High

678937

ATL4
ADAMTS-like protein 4

2

3

High-throughput

0.553

High

678939

KCTD9
BTB/POZ domain-containing protein KCTD9

2

8

High-throughput

0.553

High

678945

DZIP3
E3 ubiquitin-protein ligase DZIP3

2

2

High-throughput

0.553

High

678946

KR111
Keratin-associated protein 11-1

2

1

High-throughput

0.553

High

678948

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

678951

TRI42
Tripartite motif-containing protein 42

2

19

High-throughput

0.553

High

678954

CEP70
Centrosomal protein of 70 kDa

2

1

High-throughput

0.553

High

678960

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.553

High

678969

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

6

High-throughput

0.553

High

678979

LR2BP
LRP2-binding protein

2

3

High-throughput

0.553

High

257571

ANR17
Ankyrin repeat domain-containing protein 17

1

19

High-throughput

0.536

High

539779

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

678885

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.536

High

678963

ARK2N
Protein ARK2N

1

1

High-throughput

0.536

High

678964

HES6
Transcription cofactor HES-6

1

7

High-throughput

0.536

High

678899

BTG2
Protein BTG2

1

2

Small-scale

0.501

High

678942

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

678950

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

19

High-throughput

0.489

High

678967

ACBD6
Acyl-CoA-binding domain-containing protein 6

1

20

High-throughput

0.489

High

678973

MMAD
Cobalamin trafficking protein CblD

1

1

High-throughput

0.489

High

678907

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

High-throughput

0.481

High

678952

ZNF34
Zinc finger protein 34

1

3

High-throughput

0.481

High

678958

TSC1
Hamartin

1

3

High-throughput

0.481

High

678959

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

20

High-throughput

0.481

High

337365

ABL1
Tyrosine-protein kinase ABL1

1

10

High-throughput

0.479

High

379054

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.479

High

412045

FYN
Tyrosine-protein kinase Fyn

1

10

High-throughput

0.479

High

522809

SRC
Proto-oncogene tyrosine-protein kinase Src

1

10

High-throughput

0.479

High

557620

NCK1
SH2/SH3 adapter protein NCK1

1

14

High-throughput

0.479

High

678897

GRB2
Growth factor receptor-bound protein 2

1

11

High-throughput

0.479

High

678901

IRF8
Interferon regulatory factor 8

1

6

Small-scale

0.479

High

678902

KMT2A
Histone-lysine N-methyltransferase 2A

1

11

Small-scale

0.479

High

678903

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

678911

SMAD4
Mothers against decapentaplegic homolog 4

1

12

Small-scale

0.479

High

57981

A2RRN7
CADPS protein

1

3

High-throughput

0.470

High

484573

NT2NC
Notch homolog 2 N-terminal-like protein C

1

15

High-throughput

0.470

High

678922

KRA63
Keratin-associated protein 6-3

1

5

High-throughput

0.470

High

678925

Q49AR9
ANKS1A protein

1

8

High-throughput

0.470

High

678944

Q86WV8
TSC complex subunit 1

1

2

High-throughput

0.470

High

678949

Q8IV28
NID2 protein

1

4

High-throughput

0.470

High

320988

PTBP3
Polypyrimidine tract-binding protein 3

1

2

High-throughput

0.445

High

587437

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

High-throughput

0.445

High

485

NBPFJ
Neuroblastoma breakpoint family member 19

1

5

High-throughput

0.439

High

678912

NID2
Nidogen-2

1

4

High-throughput

0.439

High

678914

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.439

High

678924

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

1

High-throughput

0.439

High

678941

NT2NA
Notch homolog 2 N-terminal-like protein A

1

14

High-throughput

0.439

High

678985

CAPS1
Calcium-dependent secretion activator 1

1

3

High-throughput

0.439

High

678913

SNX17
Sorting nexin-17

3

0

High-throughput

0.346

High

63296

MET15
12S rRNA N4-methylcytidine

2

0

High-throughput

0.316

High

678888

FNTB
Protein farnesyltransferase subunit beta

2

0

High-throughput

0.316

High

678918

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

678919

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

678928

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

678938

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

678947

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

678953

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.316

High

678968

CCM2
Cerebral cavernous malformations 2 protein

2

0

High-throughput

0.316

High

678974

GSTO2
Glutathione S-transferase omega-2

2

0

High-throughput

0.316

High

678933

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.279

Low

678940

MIGA2
Mitoguardin 2

1

0

High-throughput

0.279

Low

678926

KHDC1
KH homology domain-containing protein 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024