Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: TWF2 (Q6IBS0)
Twinfilin-2 (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like) (Twinfilin-1-like protein)
Gene: TWF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 17353931, 35271311
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cofilin_ADF~F_actin_cap_B
Common GO terms GO:0010591 - regulation of lamellipodium assembly
GO:0030027 - lamellipodium
GO:0045296 - cadherin binding
GO:0051015 - actin filament binding
GO:0051016 - barbed-end actin filament capping
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 272
Hs

1 349
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024