HitPredict

Interactor 1: COPD (P48444)
Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)
Gene: ARCN1

Interactor 2: TMEDA (P49755)
Transmembrane emp24 domain-containing protein 10 (Protein TMED10) (21 kDa transmembrane-trafficking protein) (S31I125) (S31III125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta)
Gene: TMED10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	9751720, 9472029, 35271311
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum and 2 others more... GO:0016020 - membrane GO:0030133 - transport vesicle
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 511 Hs			1 219
+	Hs
		819006 COPD_HUMAN (1-511): 0: 828: 100.00		TMED9_HUMAN (8-218): 4.55e-80: 241: 29.96
+	Hs
		818943 COPD_HUMAN (1-511): 0: 828: 100.00		TMED2_HUMAN (30-218): 4.01e-67: 206: 20.53
+	Hs
		819050 COPD_HUMAN (1-511): 0: 828: 100.00		TMED5_HUMAN (24-216): 5.38e-56: 179: 17.16
+	Sc
		798119 COPD_YEAST (1-510): 8.87e-169: 489: 30.85		ERP1_YEAST (16-218): 9.62e-59: 185: 19.72
+	Sc
		798109 COPD_YEAST (1-510): 8.87e-169: 489: 30.85		TMEDA_YEAST (18-218): 2.52e-57: 182: 35.75