Interactor 1: UHRF1 (B6CHA3)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear zinc finger protein Np95) (XNp95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1
Interactor 2: P79922 (P79922)
DNA (cytosine-5)-methyltransferase (EC 2.1.1.37)
Gene: dnmt1.L
Species: Xenopus laevis
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32144273 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BAH~PHD, DNMT1-RFD~ubiquitin |
| Common GO terms | GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0044027 - negative regulation of gene expression via chromosomal CpG island methylation |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
