HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26091241, 25900982
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 605
+	Hs
		821077 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1127733 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		820867 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		990957 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1377170 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		807876 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1219809 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Mm
		541461 MAP1B_MOUSE (491-2148): 8.51e-41: 168: 8.67		LIS1_MOUSE (174-494): 5.84e-74: 244: 21.37
+	Hs
		990904 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1281391 PRR36_HUMAN (1188-2157): 2.19e-28: 127: 12.22		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		793042 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		903374 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1346970 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		903354 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1302927 MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		1346974 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		209436 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		152622 KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		245652 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13
+	Hs
		1309170 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		TBL1Y_HUMAN (501-605): 2.08e-14: 78.1: 20.00