HitPredict - High confidence protein-protein interactions

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.943

Property	Details
Experiments	33961781, 35271311, 37071682, 36652389, 24981860, 35235311
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0005813 - centrosome GO:0005829 - cytosol GO:0005832 - chaperonin-containing T-complex GO:0005874 - microtubule and 14 others more... GO:0006457 - protein folding GO:0007339 - binding of sperm to zona pellucida GO:0016887 - ATP hydrolysis activity GO:0032212 - positive regulation of telomere maintenance via telomerase GO:0044183 - protein folding chaperone GO:0044297 - cell body GO:0050821 - protein stabilization GO:0051082 - unfolded protein binding GO:0061077 - chaperone-mediated protein folding GO:0070062 - extracellular exosome GO:0140662 - ATP-dependent protein folding chaperone GO:1904851 - positive regulation of establishment of protein localization to telomere GO:1904871 - positive regulation of protein localization to Cajal body GO:1904874 - positive regulation of telomerase RNA localization to Cajal body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	541
Hs

1	539

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Last updated: 15 Jul 2024