HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	26496610, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 309
+	Hs
		821161 TCPE_HUMAN (1-541): 0: 635: 100.00		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		821143 TCPE_HUMAN (1-541): 0: 635: 100.00		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Hs
		826610 TCPG_HUMAN (14-540): 0: 572: 33.15		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		826603 TCPG_HUMAN (14-540): 0: 572: 33.15		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Hs
		930969 TCPH_HUMAN (12-539): 0: 570: 29.64		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		915267 TCPH_HUMAN (12-539): 0: 570: 29.64		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Sc
		618779 TCPE_YEAST (3-540): 0: 582: 59.89		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Hs
		826591 TCPG_HUMAN (14-540): 0: 572: 33.15		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Hs
		890997 TCPH_HUMAN (12-539): 0: 570: 29.64		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Hs
		573211 TCPA_HUMAN (26-541): 0: 545: 32.08		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		573203 TCPA_HUMAN (26-541): 0: 545: 32.08		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Sc
		618845 TCPH_YEAST (7-540): 0: 542: 30.30		PP2A2_YEAST (9-309): 0: 531: 76.08
+	Sc
		618836 TCPG_YEAST (12-541): 0: 540: 31.98		PP2A2_YEAST (9-309): 0: 531: 76.08
+	Sc
		618781 TCPH_YEAST (7-540): 0: 542: 30.30		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Sc
		618772 TCPG_YEAST (12-541): 0: 540: 31.98		PP2A1_YEAST (7-309): 0: 519: 74.92
+	Hs
		573192 TCPA_HUMAN (26-541): 0: 545: 32.08		PP4C_HUMAN (4-309): 0: 511: 64.50
+	Sc
		594329 TCPE_YEAST (3-540): 0: 582: 59.89		PP11_YEAST (11-309): 4.65e-139: 397: 58.03
+	Sc
		594334 TCPH_YEAST (7-540): 0: 542: 30.30		PP11_YEAST (11-309): 4.65e-139: 397: 58.03
+	Sc
		594322 TCPG_YEAST (12-541): 0: 540: 31.98		PP11_YEAST (11-309): 4.65e-139: 397: 58.03
+	Hs
		843130 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		PP4C_HUMAN (4-309): 0: 511: 64.50