HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: CDC20 (Q12834)
Cell division cycle protein 20 homolog (p55CDC)
Gene: CDC20

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.711

Property	Details
Experiments	33961781, 25306918, 26811472, 28096334, 23443559
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 499
+	Hs
		826632 TCPG_HUMAN (14-540): 0: 572: 33.15		CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00
+	Hs
		1017427 TCPH_HUMAN (12-539): 0: 570: 29.64		CDC20_HUMAN (1-499): 1.18e-136: 405: 100.00
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (64-471): 2.26e-89: 283: 18.93
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (210-496): 2.2e-71: 242: 17.81
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (340-499): 1.5e-30: 123: 20.25
+	Hs
		821460 TCPE_HUMAN (1-541): 0: 635: 100.00		FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (55-254): 8.3e-18: 86.5: 9.66
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (337-498): 1.74e-37: 143: 16.56
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (51-218): 4.24e-13: 73.1: 10.92
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (434-498): 5.08e-13: 72.7: 21.54
+	Hs
		821392 TCPE_HUMAN (1-541): 0: 635: 100.00		KTNB1_HUMAN (321-470): 1.17e-09: 62.8: 30.26
+	Hs
		826938 TCPG_HUMAN (14-540): 0: 572: 33.15		FZR1_HUMAN (315-495): 1.51e-24: 108: 19.02
+	Sc
		640846 TCPE_YEAST (3-540): 0: 582: 59.89		CDC20_YEAST (315-495): 5.18e-14: 76.6: 18.13
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (55-254): 8.3e-18: 86.5: 9.66
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (55-254): 8.3e-18: 86.5: 9.66
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (51-218): 4.24e-13: 73.1: 10.92
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (434-498): 5.08e-13: 72.7: 21.54
+	Hs
		1240450 TCPH_HUMAN (12-539): 0: 570: 29.64		POC1A_HUMAN (434-498): 5.08e-13: 72.7: 21.54
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (431-499): 4.68e-12: 69.2: 24.64
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (431-499): 4.68e-12: 69.2: 24.64