Protein: K2C4
Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Type-II keratin Kb4)

Gene: K2C4, KRT4
Organism: Homo sapiens
Interactions: 45
UniProt ID: P19013

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0007010 - cytoskeleton organization
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

300726

KRT38
Keratin, type I cuticular Ha8

4

20

High-throughput

0.883

High

618140

KT33B
Keratin, type I cuticular Ha3-II

3

20

High-throughput

0.845

High

618147

K1C40
Keratin, type I cytoskeletal 40

3

20

High-throughput

0.845

High

617997

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.789

High

566238

K1C13
Keratin, type I cytoskeletal 13

2

20

High-throughput

0.770

High

49881

A1A4E9
Keratin 13

1

20

High-throughput

0.665

High

300549

KRT36
Keratin, type I cuticular Ha6

1

20

High-throughput

0.665

High

300626

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.665

High

475516

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.665

High

476265

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.665

High

618142

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.665

High

618143

K1C24
Keratin, type I cytoskeletal 24

1

20

High-throughput

0.665

High

618148

K1C28
Keratin, type I cytoskeletal 28

1

20

High-throughput

0.665

High

618149

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.665

High

618150

K1C25
Keratin, type I cytoskeletal 25

1

20

High-throughput

0.665

High

618157

KRT35
Keratin, type I cuticular Ha5

1

20

High-throughput

0.665

High

618141

NUMA1
Nuclear mitotic apparatus protein 1

2

10

High-throughput

0.571

High

618160

TRI54
Tripartite motif-containing protein 54

2

20

High-throughput

0.544

High

618151

CEP57
Centrosomal protein of 57 kDa

1

4

High-throughput

0.515

High

618158

ASPP1
Apoptosis-stimulating of p53 protein 1

1

5

High-throughput

0.515

High

618163

CN119
Uncharacterized protein C14orf119

1

1

High-throughput

0.515

High

618165

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.515

High

618144

CCD57
Coiled-coil domain-containing protein 57

1

4

High-throughput

0.470

High

284540

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.445

High

317133

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

2

High-throughput

0.445

High

395464

ESR1
Estrogen receptor

1

15

High-throughput

0.445

High

488400

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

10

High-throughput

0.445

High

618135

EPIPL
Epiplakin

1

20

High-throughput

0.445

High

618137

SQSTM
Sequestosome-1

1

7

High-throughput

0.445

High

618138

CUL3
Cullin-3

1

20

High-throughput

0.445

High

618152

KIBRA
Protein KIBRA

1

18

High-throughput

0.445

High

618154

THOC2
THO complex subunit 2

1

2

High-throughput

0.445

High

618155

FAN
Protein FAN

1

5

High-throughput

0.445

High

618156

ESR2
Estrogen receptor beta

1

15

High-throughput

0.445

High

618161

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

618162

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

15

High-throughput

0.445

High

618166

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

4

High-throughput

0.445

High

618164

UXT
Protein UXT

1

0

Small-scale

0.426

High

618167

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.426

High

618136

LG3BP
Galectin-3-binding protein

1

9

High-throughput

0.407

High

618139

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.407

High

618146

USPL1
SUMO-specific isopeptidase USPL1

1

1

High-throughput

0.407

High

618153

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.407

High

618159

SLX1
Structure-specific endonuclease subunit SLX1

1

2

High-throughput

0.407

High

618145

SLX4I
Protein SLX4IP

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025