HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: EIF2A (Q9BY44)
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]
Gene: EIF2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 585
+	Hs
		1306661 TCPH_HUMAN (12-539): 0: 570: 29.64		EIF2A_HUMAN (1-573): 3.48e-165: 484: 100.00
+	Sc
		410123 TCPG_YEAST (12-541): 0: 540: 31.98		EIF3B_YEAST (14-500): 5.79e-101: 324: 15.37
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60
+	Hs
		821392 TCPE_HUMAN (1-541): 0: 635: 100.00		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (355-490): 1.49e-10: 65.6: 8.09
+	Hs
		826848 TCPG_HUMAN (14-540): 0: 572: 33.15		TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60
+	Hs
		1306645 TCPH_HUMAN (12-539): 0: 570: 29.64		TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (310-529): 2.68e-16: 83.3: 13.51
+	Hs
		1306654 TCPH_HUMAN (12-539): 0: 570: 29.64		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		573446 TCPA_HUMAN (26-541): 0: 545: 32.08		TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (282-449): 2.09e-13: 73.7: 13.22
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (282-449): 2.09e-13: 73.7: 13.22
+	Hs
		1306704 TCPH_HUMAN (12-539): 0: 570: 29.64		NLE1_HUMAN (355-490): 1.49e-10: 65.6: 8.09
+	Hs
		573456 TCPA_HUMAN (26-541): 0: 545: 32.08		KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27
+	Hs
		573201 TCPA_HUMAN (26-541): 0: 545: 32.08		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09
+	Hs
		573346 TCPA_HUMAN (26-541): 0: 545: 32.08		WDR5B_HUMAN (282-449): 2.09e-13: 73.7: 13.22
+	Hs
		843139 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09