HitPredict

Interactor 1: ERKA (P40417)
Mitogen-activated protein kinase ERK-A (EC 2.7.11.24) (Extracellular-regulated kinase A) (Protein rolled)
Gene: rl

Interactor 2: ERKA (P40417)
Mitogen-activated protein kinase ERK-A (EC 2.7.11.24) (Extracellular-regulated kinase A) (Protein rolled)
Gene: rl

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.43 1.00 0.656

The method score is based on:

Property Details
Experiments 14605208
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0000278 - mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
and 43 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 376
Dm

1 376
+ Hs
+ Mm
+ Rn
+ Hs
+ Rn
+ At
+ Hs
+ At
+ At
+ Hs
+ An
+ At
+ Zm
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025