HitPredict

Interactor 1: AMPH (P49418)
Amphiphysin
Gene: AMPH

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	10542231
Identification Methods	peptide array
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 695 Hs			1 869
+	Hs
		827729 AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Mm
		1186718 AMPH_MOUSE (1-695): 5.33e-119: 373: 82.90		DYN3_MOUSE (1-869): 0: 1071: 95.99
+	Hs
		827736 AMPH_HUMAN (1-695): 5.58e-133: 409: 100.00		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		760477 AMPH_MOUSE (1-695): 5.33e-119: 373: 82.90		DYN2_MOUSE (1-869): 0: 1038: 79.21
+	Mm
		760459 AMPH_MOUSE (1-695): 5.33e-119: 373: 82.90		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Rn
		139974 AMPH_RAT (1-695): 6.91e-115: 362: 84.75		DYN2_RAT (1-869): 0: 1037: 79.09
+	Rn
		139973 AMPH_RAT (1-695): 6.91e-115: 362: 84.75		DYN1_RAT (1-852): 0: 1028: 78.22
+	Hs
		1167839 DNMBP_HUMAN (12-536): 5.06e-55: 206: 18.97		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		840739 DNMBP_HUMAN (12-536): 5.06e-55: 206: 18.97		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		983387 DNMBP_HUMAN (12-536): 5.06e-55: 206: 18.97		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		139042 BIN1_MOUSE (372-695): 1.35e-34: 141: 23.15		DYN3_MOUSE (1-869): 0: 1071: 95.99
+	Mm
		139029 BIN1_MOUSE (372-695): 1.35e-34: 141: 23.15		DYN2_MOUSE (1-869): 0: 1038: 79.21
+	Hs
		131222 BIN1_HUMAN (375-694): 1.37e-32: 135: 23.44		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Mm
		139028 BIN1_MOUSE (372-695): 1.35e-34: 141: 23.15		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Hs
		131238 BIN1_HUMAN (375-694): 1.37e-32: 135: 23.44		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Rn
		139987 BIN1_RAT (372-695): 8.26e-34: 139: 23.15		DYN1_RAT (1-852): 0: 1028: 78.22
+	Hs
		983422 CABIN_HUMAN (291-589): 2.25e-12: 72.8: 12.87		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Ce
		105220 G5ECK4_CAEEL (12-625): 5.15e-33: 138: 15.04		DYN1_CAEEL (3-815): 0: 947: 62.09
+	Sc
		599466 RV167_YEAST (11-424): 3.83e-41: 158: 15.63		VPS1_YEAST (7-745): 0: 605: 34.31