Protein: TRI45
E3 ubiquitin-protein ligase TRIM45 (EC 2.3.2.27) (RING finger protein 99)

Gene: TRI45, TRIM45
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q9H8W5

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

906784

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

Small-scale

0.767

High

1413492

AASD1
Alanyl-tRNA editing protein Aarsd1

4

9

High-throughput

0.698

High

952349

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

3

12

High-throughput

0.647

High

990990

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

20

Small-scale

0.647

High

1436631

TRI45
E3 ubiquitin-protein ligase TRIM45

1

18

Small-scale

0.647

High

1436634

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

20

Small-scale

0.634

High

909390

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.621

High

957201

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.621

High

982323

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

Small-scale

0.621

High

1381202

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

Small-scale

0.621

High

1397293

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

Small-scale

0.621

High

1436636

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

Small-scale

0.621

High

1290973

TAXB1
Tax1-binding protein 1

2

20

High-throughput

0.606

High

1388501

ZMY19
Zinc finger MYND domain-containing protein 19

2

1

High-throughput

0.606

High

1398714

AP4AT
AP-4 complex accessory subunit Tepsin

2

2

High-throughput

0.606

High

1436635

TFP11
Tuftelin-interacting protein 11

2

6

High-throughput

0.606

High

1413629

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.580

High

1410877

MGME1
Mitochondrial genome maintenance exonuclease 1

2

1

High-throughput

0.574

High

992964

RACK1
Small ribosomal subunit protein RACK1

1

17

Small-scale

0.561

High

138875

STK25
Serine/threonine-protein kinase 25

1

20

High-throughput

0.536

High

1434681

RABE2
Rab GTPase-binding effector protein 2

1

17

High-throughput

0.536

High

1436632

COG4
Conserved oligomeric Golgi complex subunit 4

1

1

High-throughput

0.536

High

1436633

ZBT40
Zinc finger and BTB domain-containing protein 40

1

20

High-throughput

0.536

High

1096226

TADBP
TAR DNA-binding protein 43

1

20

High-throughput

0.515

High

955609

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.501

High

894173

MEOX2
Homeobox protein MOX-2

1

16

High-throughput

0.481

High

214039

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

12

Small-scale

0.479

High

414641

P53
Cellular tumor antigen p53

1

15

Small-scale

0.479

High

613185

EGR1
Early growth response protein 1

1

20

High-throughput

0.479

High

827929

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.479

High

1153118

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

6

Small-scale

0.479

High

1436637

TRAF6
TNF receptor-associated factor 6

1

19

Small-scale

0.479

High

1232582

Q6FHY5
MEOX2 protein

1

19

High-throughput

0.470

High

1339960

O56A1
Olfactory receptor 56A1

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025