HitPredict

Interactor 1: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Interactor 2: MARH1 (Q8TCQ1)
E3 ubiquitin-protein ligase MARCHF1 (EC 2.3.2.27) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I) (RING finger protein 171) (RING-type E3 ubiquitin transferase MARCHF1)
Gene: MARCHF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14722266
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 289
+	Hs
		849378 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH1_HUMAN (1-289): 9.9e-118: 341: 100.00
+	Hs
		849338 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH8_HUMAN (13-289): 8.39e-90: 270: 65.04
+	Hs
		895806 UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38		MARH8_HUMAN (13-289): 8.39e-90: 270: 65.04
+	Hs
		828037 UB2R1_HUMAN (1-236): 1.98e-95: 280: 100.00		MARH2_HUMAN (21-239): 4.71e-55: 180: 24.20
+	Hs
		1199325 UB2D4_HUMAN (9-167): 3e-71: 216: 32.50		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		919767 UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		895832 UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38		MARH3_HUMAN (18-287): 4.08e-59: 190: 22.10
+	Hs
		849469 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH4_HUMAN (69-285): 3.34e-55: 185: 23.58
+	Hs
		849466 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH2_HUMAN (21-239): 4.71e-55: 180: 24.20
+	Hs
		849461 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		919880 UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		231862 UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00		MARH6_HUMAN (72-228): 3.96e-33: 130: 24.56
+	Hs
		895930 UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38		MARH5_HUMAN (80-255): 1.76e-36: 133: 18.65
+	Hs
		231861 UB2G1_HUMAN (8-176): 4.53e-68: 208: 47.93		MARH6_HUMAN (72-228): 3.96e-33: 130: 24.56
+	Hs
		231858 UB2G2_HUMAN (5-164): 8.53e-66: 203: 46.58		MARH6_HUMAN (72-228): 3.96e-33: 130: 24.56
+	Sc
		771583 UBC7_YEAST (5-157): 3.8e-65: 201: 45.75		DOA10_YEAST (71-208): 2.47e-28: 116: 19.48
+	Hs
		849448 UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78
+	Hs
		919864 UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78
+	Hs
		895915 UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38		MARH7_HUMAN (22-132): 5.41e-23: 100: 27.78