HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: GLYR1 (Q49A26)
Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1)
Gene: GLYR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 553
+	Hs
		934827 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		GLYR1_HUMAN (1-553): 0: 580: 100.00
+	Hs
		1086171 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		GLYR1_HUMAN (1-553): 0: 580: 100.00
+	Hs
		952374 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		GLYR1_HUMAN (1-553): 0: 580: 100.00
+	Hs
		828177 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		MSH6_HUMAN (2-327): 2.81e-46: 176: 14.76
+	Hs
		855452 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		MSH6_HUMAN (2-327): 2.81e-46: 176: 14.76
+	Hs
		111558 K7EK07_HUMAN (5-133): 2.58e-51: 161: 49.23		MSH6_HUMAN (2-327): 2.81e-46: 176: 14.76
+	Hs
		855454 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		MSH6_HUMAN (2-327): 2.81e-46: 176: 14.76
+	Hs
		265969 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PSIP1_HUMAN (5-267): 2.02e-43: 163: 17.92
+	Hs
		265990 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PSIP1_HUMAN (5-267): 2.02e-43: 163: 17.92
+	Hs
		265993 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		PSIP1_HUMAN (5-267): 2.02e-43: 163: 17.92
+	Hs
		850895 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGF_HUMAN (5-217): 1.6e-43: 156: 27.91
+	Hs
		935417 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGR3_HUMAN (6-128): 5.98e-44: 156: 32.06
+	Hs
		850901 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		HDGF_HUMAN (5-217): 1.6e-43: 156: 27.91
+	Hs
		828282 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		HDGR2_HUMAN (5-206): 1.34e-28: 122: 20.71
+	Hs
		934923 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGR2_HUMAN (5-206): 1.34e-28: 122: 20.71
+	Hs
		1174587 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		HDGR2_HUMAN (5-206): 1.34e-28: 122: 20.71
+	Hs
		952434 H33_HUMAN (5-134): 1.57e-51: 161: 49.62		HDGR2_HUMAN (5-206): 1.34e-28: 122: 20.71
+	Hs
		828350 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		NSD1_HUMAN (10-135): 3.41e-15: 81.4: 19.55
+	Hs
		935129 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		NSD1_HUMAN (10-135): 3.41e-15: 81.4: 19.55
+	Hs
		1086280 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		NSD1_HUMAN (10-135): 3.41e-15: 81.4: 19.55