HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: RBM7 (Q9Y580)
RNA-binding protein 7 (RNA-binding motif protein 7)
Gene: RBM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 266
+	Hs
		625657 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Hs
		516416 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		111287 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		J3KPD3_HUMAN (1-266): 1.94e-56: 183: 99.63
+	Hs
		834033 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		PABP4_HUMAN (4-262): 1.83e-39: 146: 15.14
+	Hs
		516417 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		834049 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBY1F_HUMAN (5-265): 1.01e-37: 140: 21.29
+	Hs
		483432 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		RBY1A_HUMAN (5-265): 1.26e-37: 139: 21.29
+	Hs
		516362 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		833874 CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		834030 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		625400 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		1031320 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		PABP4_HUMAN (4-262): 1.83e-39: 146: 15.14
+	Hs
		516508 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		1020254 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		642764 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		ELAV4_HUMAN (3-92): 2.27e-21: 94: 28.57
+	Hs
		1043793 DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50		ELAV3_HUMAN (2-216): 6.03e-19: 87: 15.14