Interactor 1: CLK3 (P49761)
Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)
Gene: CLK3
Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.941 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 33961781, 32707033, 34133714, 23602568 |
| Identification Methods | two hybrid, affinity chromatography technology, enzymatic study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, pull down, protein kinase assay |
| Interaction Type | direct interaction, physical association, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0003723 - RNA binding GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 3 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
