HitPredict

Interactor 1: PRS8 (P41836)
26S proteasome regulatory subunit 8 homolog (Protein let1)
Gene: let1

Interactor 2: RPN6 (Q9P7S2)
Probable 26S proteasome regulatory subunit rpn6
Gene: RPN6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22187461
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Sp			1 421
+	Sp
		267654 PRS10_SCHPO (21-401): 8.96e-155: 443: 45.29		RPN6_SCHPO (1-421): 1.51e-105: 320: 100.00
+	Hs
		127923 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Dm
		874971 PRS4_DROME (7-395): 3.14e-134: 393: 44.22		PSD11_DROME (1-419): 5.23e-105: 319: 52.61
+	At
		1442344 PRS4A_ARATH (7-393): 1.79e-133: 391: 45.22		PSD11_ARATH (1-420): 1.46e-101: 310: 48.81
+	Hs
		127924 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Hs
		127899 PRS6B_HUMAN (10-399): 5.59e-124: 366: 41.80		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Hs
		958616 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		CSN2_HUMAN (11-417): 4.2e-94: 291: 20.53
+	Dm
		1267339 Q9V405_DROME (1-399): 1.28e-122: 362: 40.60		PSD11_DROME (1-419): 5.23e-105: 319: 52.61
+	Hs
		968705 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		958617 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		CSN2_HUMAN (11-417): 4.2e-94: 291: 20.53
+	Hs
		127895 PRS7_HUMAN (80-388): 2.38e-112: 337: 56.31		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Hs
		128196 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Dm
		874994 PRS4_DROME (7-395): 3.14e-134: 393: 44.22		PSMD6_DROME (27-419): 1.74e-81: 257: 13.86
+	Hs
		968923 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		851321 PRS6B_HUMAN (10-399): 5.59e-124: 366: 41.80		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		128197 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Hs
		128172 PRS6B_HUMAN (10-399): 5.59e-124: 366: 41.80		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Dm
		1463474 Q9V405_DROME (1-399): 1.28e-122: 362: 40.60		PSMD6_DROME (27-419): 1.74e-81: 257: 13.86
+	At
		1373147 PRS4A_ARATH (7-393): 1.79e-133: 391: 45.22		PSMD6_ARATH (57-411): 5.62e-70: 227: 13.41
+	Dm
		874993 PRS4_DROME (7-395): 3.14e-134: 393: 44.22		CSN4_DROME (50-413): 1.59e-66: 219: 15.13