HitPredict

Interactor 1: ELK3 (P41970)
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)
Gene: ELK3

Interactor 2: ASXL1 (Q8IXJ9)
Polycomb group protein ASXL1 (Additional sex combs-like protein 1)
Gene: ASXL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	32683582
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 1541
+	Hs
		1152709 ELF2_HUMAN (4-376): 4.15e-38: 146: 23.14		ASXL1_HUMAN (1-1541): 0: 2382: 100.00
+	Hs
		1312420 ELF4_HUMAN (3-398): 1.97e-32: 131: 22.87		ASXL1_HUMAN (1-1541): 0: 2382: 100.00
+	Hs
		1152703 ELF2_HUMAN (4-376): 4.15e-38: 146: 23.14		ASXL2_HUMAN (1474-1541): 1.15e-23: 111: 55.88
+	Hs
		738999 ELF1_HUMAN (4-377): 3.48e-34: 136: 20.78		ASXL2_HUMAN (1474-1541): 1.15e-23: 111: 55.88
+	Hs
		1260618 ELF4_HUMAN (3-398): 1.97e-32: 131: 22.87		ASXL2_HUMAN (1474-1541): 1.15e-23: 111: 55.88
+	Hs
		1260617 FEV_HUMAN (3-174): 2.98e-32: 123: 32.96		ASXL2_HUMAN (1474-1541): 1.15e-23: 111: 55.88
+	Hs
		540899 ERG_HUMAN (3-164): 7.29e-30: 122: 37.58		ASXL2_HUMAN (1474-1541): 1.15e-23: 111: 55.88