Protein: ELF4
ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)

Gene: ELF4
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q99607

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001787 - natural killer cell proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045685

TF65
Transcription factor p65

2

13

Small-scale

0.754

High

1029918

RUNX1
Runt-related transcription factor 1

2

4

Small-scale

0.624

High

1017474

FOXK1
Forkhead box protein K1

1

15

High-throughput

0.618

High

1055634

GABPA
GA-binding protein alpha chain

1

18

High-throughput

0.618

High

1152732

ELF2
ETS-related transcription factor Elf-2

1

16

High-throughput

0.618

High

1396288

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

High-throughput

0.618

High

1405630

ELF4
ETS-related transcription factor Elf-4

1

15

Small-scale

0.618

High

447349

NPM
Nucleophosmin

1

1

Small-scale

0.561

High

1101882

SKP2
S-phase kinase-associated protein 2

1

11

Small-scale

0.561

High

1029367

SET
Protein SET

1

1

High-throughput

0.541

High

1156700

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.541

High

378380

IFNB
Interferon beta

1

1

Small-scale

0.515

High

714377

PML
Protein PML

1

17

Small-scale

0.515

High

701213

PSB5
Proteasome subunit beta type-5

1

2

High-throughput

0.500

High

938276

SEC13
Protein SEC13 homolog

1

14

High-throughput

0.500

High

1040198

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

6

High-throughput

0.500

High

1323135

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

High-throughput

0.500

High

1405631

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

13

High-throughput

0.500

High

65805

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

3

High-throughput

0.479

High

130792

TAF4
Transcription initiation factor TFIID subunit 4

1

15

High-throughput

0.479

High

161505

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

175921

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

180910

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

194604

KDM6A
Lysine-specific demethylase 6A

1

8

High-throughput

0.479

High

282771

E2F6
Transcription factor E2F6

1

6

High-throughput

0.479

High

283539

TAD2A
Transcriptional adapter 2-alpha

1

19

High-throughput

0.479

High

284977

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

18

High-throughput

0.479

High

519553

MYBB
Myb-related protein B

1

6

High-throughput

0.479

High

675644

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.479

High

892064

TAF6
Transcription initiation factor TFIID subunit 6

1

5

High-throughput

0.479

High

903239

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

High-throughput

0.479

High

926682

HIRA
Protein HIRA

1

14

High-throughput

0.479

High

927514

ATX1
Ataxin-1

1

10

High-throughput

0.479

High

980202

H4
Histone H4

1

3

High-throughput

0.479

High

1034882

SP2
Transcription factor Sp2

1

20

High-throughput

0.479

High

1053306

MBTD1
MBT domain-containing protein 1

1

12

High-throughput

0.479

High

1086810

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

1145513

RBBP5
Retinoblastoma-binding protein 5

1

11

High-throughput

0.479

High

1149792

TAF5
Transcription initiation factor TFIID subunit 5

1

15

High-throughput

0.479

High

1155318

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

6

High-throughput

0.479

High

1157602

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

1195590

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1196906

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

8

High-throughput

0.479

High

1198111

EPC2
Enhancer of polycomb homolog 2

1

3

High-throughput

0.479

High

1212443

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.479

High

1218892

TAF3
Transcription initiation factor TFIID subunit 3

1

20

High-throughput

0.479

High

1228272

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

1236072

LIN54
Protein lin-54 homolog

1

4

High-throughput

0.479

High

1241286

TAF2
Transcription initiation factor TFIID subunit 2

1

4

High-throughput

0.479

High

1242492

NFRKB
Nuclear factor related to kappa-B-binding protein

1

19

High-throughput

0.479

High

1250457

MCAF1
Activating transcription factor 7-interacting protein 1

1

20

High-throughput

0.479

High

1253865

SRCAP
Helicase SRCAP

1

20

High-throughput

0.479

High

1260618

ASXL2
Putative Polycomb group protein ASXL2

1

20

High-throughput

0.479

High

1276096

KANL1
KAT8 regulatory NSL complex subunit 1

1

2

High-throughput

0.479

High

1277222

POGZ
Pogo transposable element with ZNF domain

1

4

High-throughput

0.479

High

1278966

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

1287978

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

1292867

STING
Stimulator of interferon genes protein

1

1

Small-scale

0.479

High

1310116

MGAP
MAX gene-associated protein

1

8

High-throughput

0.479

High

1312420

ASXL1
Polycomb group protein ASXL1

1

7

High-throughput

0.479

High

1315044

ZZZ3
ZZ-type zinc finger-containing protein 3

1

1

High-throughput

0.479

High

1323533

ZN687
Zinc finger protein 687

1

4

High-throughput

0.479

High

1337579

SP20H
Transcription factor SPT20 homolog

1

2

High-throughput

0.479

High

1338923

NUP43
Nucleoporin Nup43

1

12

High-throughput

0.479

High

1340151

KDM2B
Lysine-specific demethylase 2B

1

17

High-throughput

0.479

High

1356502

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

1357144

GATD1
GATA zinc finger domain-containing protein 1

1

4

High-throughput

0.479

High

1364544

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

1369153

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

1369199

KAT2B
Histone acetyltransferase KAT2B

1

20

High-throughput

0.479

High

1370742

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

20

High-throughput

0.479

High

1371255

KAT5
Histone acetyltransferase KAT5

1

8

High-throughput

0.479

High

1380949

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

12

High-throughput

0.479

High

1389678

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.479

High

1390148

MCRS1
Microspherule protein 1

1

4

High-throughput

0.479

High

1392036

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

14

High-throughput

0.479

High

1393259

SENP5
Sentrin-specific protease 5

1

2

High-throughput

0.479

High

1396733

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

1401042

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

1401362

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1405632

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.479

High

1405633

ARP6
Actin-related protein 6

1

6

High-throughput

0.479

High

1405634

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.479

High

1405635

EPC1
Enhancer of polycomb homolog 1

1

3

High-throughput

0.479

High

1405637

ZN644
Zinc finger protein 644

1

10

High-throughput

0.479

High

1405638

KAT8
Histone acetyltransferase KAT8

1

8

High-throughput

0.479

High

1405639

ARP8
Actin-related protein 8

1

5

High-throughput

0.479

High

1405640

ARP5
Actin-related protein 5

1

10

High-throughput

0.479

High

1405641

KANL2
KAT8 regulatory NSL complex subunit 2

1

2

High-throughput

0.479

High

1405642

SHCAF
SIN3-HDAC complex-associated factor

1

1

High-throughput

0.479

High

1405644

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

1405645

CXXC1
CXXC-type zinc finger protein 1

1

20

High-throughput

0.479

High

1405646

KANL3
KAT8 regulatory NSL complex subunit 3

1

2

High-throughput

0.479

High

1405647

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

13

High-throughput

0.479

High

1405648

MO4L1
Mortality factor 4-like protein 1

1

3

High-throughput

0.479

High

1405649

KDM5B
Lysine-specific demethylase 5B

1

11

Small-scale

0.479

High

1405651

ZHX1
Zinc fingers and homeoboxes protein 1

1

17

High-throughput

0.479

High

1405652

INO80
Chromatin-remodeling ATPase INO80

1

20

High-throughput

0.479

High

1405653

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

1405654

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

High-throughput

0.479

High

1405655

ZN148
Zinc finger protein 148

1

12

High-throughput

0.479

High

1405656

TRRAP
Transformation/transcription domain-associated protein

1

7

High-throughput

0.479

High

1405657

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

7

High-throughput

0.479

High

1405658

ZHX2
Zinc fingers and homeoboxes protein 2

1

12

High-throughput

0.479

High

319168

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.458

High

1028354

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1244682

IN80C
INO80 complex subunit C

1

0

High-throughput

0.458

High

1405643

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

299348

FLOT1
Flotillin-1

1

10

High-throughput

0.457

High

1124895

FLOT2
Flotillin-2

1

10

High-throughput

0.457

High

1405650

TBK1
Serine/threonine-protein kinase TBK1

1

1

Small-scale

0.445

High

378258

IFNA2
Interferon alpha-2

1

1

Small-scale

0.437

High

1219740

ZMYM4
Zinc finger MYM-type protein 4

1

7

High-throughput

0.437

High

1405636

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.437

High

885707

CASP4
Caspase-4

1

0

High-throughput

0.282

High

892273

5NTC
Cytosolic purine 5'-nucleotidase

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025