HitPredict

Interactor 1: SPB8 (P50452)
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)
Gene: SERPINB8

Interactor 2: CDK15 (Q96Q40)
Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)
Gene: CDK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 374 Hs			1 435
+	Hs
		675650 ILEU_HUMAN (1-374): 1.27e-159: 454: 51.72		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00
+	Hs
		820367 SPB4_HUMAN (1-374): 3.16e-153: 438: 44.64		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00
+	Hs
		625239 SPB9_HUMAN (1-374): 1.9e-173: 489: 62.23		CDK2_HUMAN (100-398): 1.05e-141: 408: 47.51
+	Hs
		668014 SPB3_HUMAN (1-374): 7.84e-152: 435: 43.62		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00
+	Hs
		271886 SPB7_HUMAN (1-374): 1.65e-144: 416: 36.36		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00
+	Hs
		344326 AACT_HUMAN (4-374): 7.5e-141: 408: 33.25		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00
+	Hs
		738798 SPB5_HUMAN (1-374): 8.53e-141: 406: 37.73		CDK15_HUMAN (1-435): 1.3e-160: 461: 100.00