Protein: MARK4
MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1)

Gene: MARK4
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q96L34

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000930 - gamma-tubulin complex
GO:0001578 - microtubule bundle formation
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

647947

MARK3
MAP/microtubule affinity-regulating kinase 3

2

16

High-throughput

0.811

High

784068

KPCI
Protein kinase C iota type

2

10

Small-scale

0.799

High

1079132

STK11
Serine/threonine-protein kinase STK11

1

19

High-throughput

0.747

High

672244

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

7

High-throughput

0.691

High

833502

RBM25
RNA-binding protein 25

1

6

High-throughput

0.691

High

894319

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.691

High

1296782

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

Small-scale

0.687

High

982385

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

433949

LYN
Tyrosine-protein kinase Lyn

1

5

High-throughput

0.665

High

822348

KC1D
Casein kinase I isoform delta

1

8

High-throughput

0.665

High

681985

AKT1
RAC-alpha serine/threonine-protein kinase

1

14

Small-scale

0.647

High

1230021

RPTOR
Regulatory-associated protein of mTOR

1

6

Small-scale

0.647

High

1273704

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

3

Small-scale

0.646

High

614102

TBG1
Tubulin gamma-1 chain

2

3

Small-scale

0.635

High

933038

ACTS
Actin, alpha skeletal muscle

1

2

Small-scale

0.618

High

1025197

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

19

Small-scale

0.618

High

1034968

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.618

High

1183095

MARK2
Serine/threonine-protein kinase MARK2

1

15

High-throughput

0.618

High

1296784

PAR6G
Partitioning defective 6 homolog gamma

1

4

High-throughput

0.618

High

1296788

PAR6A
Partitioning defective 6 homolog alpha

1

9

High-throughput

0.618

High

497452

TAU
Microtubule-associated protein tau

2

11

Small-scale

0.602

High

909916

1433E
14-3-3 protein epsilon

2

20

Small-scale

0.601

High

927411

1433Z
14-3-3 protein zeta/delta

2

20

Small-scale

0.601

High

723381

APJ
Apelin receptor

1

0

High-throughput

0.584

High

1296786

MANS1
MANSC domain-containing protein 1

2

2

High-throughput

0.574

High

1296790

PNMA2
Paraneoplastic antigen Ma2

2

5

High-throughput

0.574

High

1071334

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.573

High

1124593

ODFP2
Outer dense fiber protein 2

1

9

Small-scale

0.561

High

263789

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.536

High

301316

MTCL2
Microtubule cross-linking factor 2

1

12

High-throughput

0.536

High

365021

FRIL
Ferritin light chain

1

2

High-throughput

0.536

High

428367

TBB5
Tubulin beta chain

1

1

Small-scale

0.536

High

573048

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.536

High

847056

SMCA4
Transcription activator BRG1

1

2

High-throughput

0.536

High

904994

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

915261

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

High-throughput

0.536

High

1069475

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

1175107

TBA1A
Tubulin alpha-1A chain

1

3

Small-scale

0.536

High

1184645

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

1

High-throughput

0.536

High

1242275

PNMA1
Paraneoplastic antigen Ma1

1

5

High-throughput

0.536

High

1268074

MY18A
Unconventional myosin-XVIIIa

1

9

High-throughput

0.536

High

1273263

ARHG2
Rho guanine nucleotide exchange factor 2

1

4

High-throughput

0.536

High

1273797

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

High-throughput

0.536

High

1296785

RNF41
E3 ubiquitin-protein ligase NRDP1

1

6

High-throughput

0.536

High

1296792

MTCL1
Microtubule cross-linking factor 1

1

12

High-throughput

0.536

High

1296793

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

3

High-throughput

0.536

High

395499

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.515

High

1191314

KCD20
BTB/POZ domain-containing protein KCTD20

1

0

High-throughput

0.513

High

1296781

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.513

High

1296783

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

1296791

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

503298

MTAP2
Microtubule-associated protein 2

1

13

Small-scale

0.501

High

654032

MAP4
Microtubule-associated protein 4

1

11

Small-scale

0.501

High

808229

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

7

High-throughput

0.501

High

825335

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.493

High

179245

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.489

High

1127116

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

7

High-throughput

0.481

High

1149291

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.481

High

1189401

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.481

High

160148

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.480

High

378134

PRIO
Major prion protein

1

0

Small-scale

0.480

High

714362

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

724967

MYH9
Myosin-9

1

8

Small-scale

0.479

High

725223

MYH10
Myosin-10

1

8

Small-scale

0.479

High

1043164

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1290799

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.479

High

1296789

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

6

High-throughput

0.479

High

987537

APLP2
Amyloid beta precursor like protein 2

1

3

High-throughput

0.470

High

904085

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.460

High

101077

APRIO
Alternative prion protein

1

1

Small-scale

0.457

High

1206137

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.438

High

164453

TRI66
Tripartite motif-containing protein 66

1

5

High-throughput

0.437

High

56707

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

267536

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

0

High-throughput

0.251

Low

1296787

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024