HitPredict

Interactor 1: LHX2 (P50458)
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)
Gene: LHX2

Interactor 2: PYGO1 (Q9Y3Y4)
Pygopus homolog 1
Gene: PYGO1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 419
+	Hs
		839836 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		CHD7_HUMAN (20-302): 2.74e-38: 149: 10.71
+	Mm
		1321961 LHX9_MOUSE (1-406): 3.76e-74: 238: 61.33		PYGO1_MOUSE (1-419): 4.87e-60: 202: 87.35
+	Hs
		839785 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		KMT2C_HUMAN (38-338): 3.64e-25: 110: 11.68
+	Hs
		903795 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		PYGO1_HUMAN (1-419): 1.15e-67: 222: 100.00
+	Hs
		1148499 LHX8_HUMAN (115-394): 4.48e-35: 134: 23.84		PYGO1_HUMAN (1-419): 1.15e-67: 222: 100.00
+	Hs
		822670 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		PYGO2_HUMAN (2-419): 4.18e-47: 168: 32.38
+	Hs
		822688 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		CHD7_HUMAN (20-302): 2.74e-38: 149: 10.71
+	Hs
		1148487 LHX8_HUMAN (115-394): 4.48e-35: 134: 23.84		PYGO2_HUMAN (2-419): 4.18e-47: 168: 32.38
+	Hs
		1281210 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		PYGO1_HUMAN (1-419): 1.15e-67: 222: 100.00
+	Hs
		1283502 ISL2_HUMAN (35-112): 4.47e-10: 62.9: 17.72		PYGO1_HUMAN (1-419): 1.15e-67: 222: 100.00
+	Hs
		822650 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		KMT2C_HUMAN (38-338): 3.64e-25: 110: 11.68
+	Hs
		899936 ISL1_HUMAN (35-106): 3.43e-09: 59.8: 19.18		PYGO1_HUMAN (1-419): 1.15e-67: 222: 100.00
+	Mm
		1321869 ISL2_MOUSE (35-112): 8.55e-10: 61.7: 17.72		PYGO1_MOUSE (1-419): 4.87e-60: 202: 87.35
+	Hs
		297853 LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58		SC24D_HUMAN (98-357): 6.31e-10: 63.5: 11.28
+	Hs
		1281174 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		PYGO2_HUMAN (2-419): 4.18e-47: 168: 32.38
+	Hs
		1310381 LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47		PYGO2_HUMAN (2-419): 4.18e-47: 168: 32.38
+	Hs
		1281194 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		CHD7_HUMAN (20-302): 2.74e-38: 149: 10.71
+	Hs
		1350240 LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47		CHD7_HUMAN (20-302): 2.74e-38: 149: 10.71
+	Hs
		1243832 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		KMT2C_HUMAN (38-338): 3.64e-25: 110: 11.68
+	Hs
		1243849 LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47		KMT2C_HUMAN (38-338): 3.64e-25: 110: 11.68