HitPredict

Interactor 1: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.972

Property	Details
Experiments	10655498, 11283351, 10688190, 23712011, 17475278, 23034805, 18832349, 12354763, 18719252, 37968396
Identification Methods	two hybrid, two hybrid pooling approach, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Rad60-SLD~UQ_con
Common GO terms	GO:0000794 - condensed nuclear chromosome GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 157 Sc			1 101
+	At
		1114967 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		SUMO2_ARATH (10-99): 1.76e-37: 123: 45.06
+	Dm
		332535 Q7KNM2_DROME (1-156): 5.99e-73: 217: 53.85		O97102_DROME (13-99): 2.66e-35: 117: 43.18
+	Sp
		140897 UBC9_SCHPO (1-156): 1.33e-68: 206: 60.90		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	At
		1114966 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		SUMO3_ARATH (9-98): 4.23e-33: 112: 37.36
+	Ce
		879079 UBC9_CAEEL (1-156): 1.98e-73: 218: 53.21		SUMO_CAEEL (12-98): 3.17e-32: 109: 39.77
+	Hs
		902509 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Mm
		930505 UBC9_MOUSE (1-156): 5.53e-69: 207: 56.41		SUMO3_MOUSE (9-99): 2.6e-36: 120: 43.48
+	At
		878960 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		SUMO1_ARATH (11-96): 1.49e-32: 110: 45.98
+	Rn
		930510 UBC9_RAT (1-156): 5.53e-69: 207: 56.41		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		102156 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		SUMO5_HUMAN (1-98): 4.98e-35: 117: 43.88
+	Hs
		879101 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		928056 UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Mm
		928242 UBC9_MOUSE (1-156): 5.53e-69: 207: 56.41		SUMO1_MOUSE (1-98): 2.09e-33: 112: 44.44
+	At
		1114930 SCE1_ARATH (2-155): 7.8e-73: 216: 59.74		Q8LCF9_ARATH (2-96): 1.45e-25: 96.3: 24.21
+	Zm
		74333 B4FC97_MAIZE (4-156): 1.48e-73: 218: 31.37		B6TQW3_MAIZE (7-96): 2.32e-23: 90.9: 28.89
+	Mm
		140343 UBC9_MOUSE (1-156): 5.53e-69: 207: 56.41		NF2IP_MOUSE (10-91): 1.16e-25: 100: 23.17
+	Hs
		102167 Q7KZS0_HUMAN (1-134): 6.66e-54: 170: 59.70		SUMO5_HUMAN (1-98): 4.98e-35: 117: 43.88
+	Hs
		928121 Q7KZS0_HUMAN (1-134): 6.66e-54: 170: 59.70		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44