HitPredict

Interactor 1: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	17922018, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0019843 - rRNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 220 Sc			1 459
+	Hs
		841454 MK67I_HUMAN (60-220): 8.14e-40: 139: 28.73		RBM34_HUMAN (10-430): 4.46e-68: 225: 26.59
+	Hs
		550250 ELAV2_HUMAN (2-173): 9.76e-30: 115: 13.48		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		1090216 ELAV2_HUMAN (2-173): 9.76e-30: 115: 13.48		PABP4_HUMAN (175-459): 2.2e-57: 202: 13.54
+	Hs
		550097 PABP1_HUMAN (82-207): 1.53e-25: 105: 15.87		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Hs
		550311 PAP1L_HUMAN (82-207): 1.12e-25: 105: 16.67		PABP1_HUMAN (175-459): 1.72e-59: 207: 14.58
+	Sc
		924309 NOP15_YEAST (1-220): 1.3e-46: 155: 100.00		NOP13_YEAST (27-400): 8.64e-41: 152: 17.73
+	Hs
		1197178 PAP1L_HUMAN (82-207): 1.12e-25: 105: 16.67		PABP3_HUMAN (175-459): 2.01e-55: 196: 14.58
+	Hs
		506127 ELAV2_HUMAN (2-173): 9.76e-30: 115: 13.48		PAB4L_HUMAN (175-459): 1.04e-51: 180: 15.28
+	Hs
		211329 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Hs
		211310 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		ELAV2_HUMAN (37-360): 2.42e-31: 125: 11.49
+	Hs
		750423 CSTF2_HUMAN (91-193): 1.45e-32: 125: 22.22		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Hs
		1090232 ELAV2_HUMAN (2-173): 9.76e-30: 115: 13.48		ELAV1_HUMAN (154-360): 6.07e-33: 128: 14.23
+	Xl
		1362166 ELAV2_XENLA (78-207): 4.81e-28: 110: 18.32		ELAV2_XENLA (50-360): 9.86e-33: 129: 13.39
+	Hs
		550137 PABP1_HUMAN (82-207): 1.53e-25: 105: 15.87		TIA1_HUMAN (273-459): 1.48e-33: 131: 12.23
+	Mm
		710979 PABP1_MOUSE (82-207): 1.59e-25: 105: 15.87		TIA1_MOUSE (273-459): 1.48e-33: 131: 12.23
+	Hs
		211325 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		SF3B4_HUMAN (269-458): 2.81e-22: 100: 14.56
+	Dm
		1470879 Q9VCY1_DROME (72-204): 1.42e-38: 138: 29.20		Q9VJG2_DROME (31-365): 3.72e-16: 82.3: 20.80
+	Hs
		750476 CSTFT_HUMAN (80-177): 2e-32: 125: 23.47		CSTF2_HUMAN (269-354): 1.5e-14: 77.7: 28.74
+	Hs
		550237 PABP1_HUMAN (82-207): 1.53e-25: 105: 15.87		TIAR_HUMAN (8-280): 1.16e-10: 64.9: 8.03