Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 29283500, 28205554
Identification Methods pull down, fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001953 - negative regulation of cell-matrix adhesion
GO:0003723 - RNA binding
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
and 30 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 156
Hs

1 156
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Service provided by Combinatics, Japan

Last updated: 11Aug2025