Protein: CDN2D
Cyclin-dependent kinase 4 inhibitor D (p19-INK4d)

Gene: CDN2D, CDKN2D
Organism: Homo sapiens
Interactions: 87
UniProt ID: P55273

Gene Ontology (top 5):
GO:0000731 - DNA synthesis involved in DNA repair
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549110

CDK4
Cyclin-dependent kinase 4

16

17

Small-scale

0.989

High

937461

CDK6
Cyclin-dependent kinase 6

14

17

Small-scale

0.986

High

937464

REL
Proto-oncogene c-Rel

2

7

High-throughput

0.783

High

798904

BRCA1
Breast cancer type 1 susceptibility protein

1

8

Small-scale

0.747

High

937465

INCA1
Protein INCA1

4

1

High-throughput

0.698

High

937476

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

14

High-throughput

0.691

High

848097

NR4A2
Nuclear receptor subfamily 4 group A member 2

4

20

High-throughput

0.683

High

937500

DHB14
L-fucose dehydrogenase

4

0

High-throughput

0.677

High

937513

IKZF3
Zinc finger protein Aiolos

3

3

High-throughput

0.672

High

652481

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

2

20

High-throughput

0.628

High

937469

FHL3
Four and a half LIM domains protein 3

1

14

High-throughput

0.621

High

937505

SHLB2
Endophilin-B2

1

9

High-throughput

0.621

High

937514

ZBT32
Zinc finger and BTB domain-containing protein 32

1

4

High-throughput

0.621

High

937515

SHLB1
Endophilin-B1

1

14

High-throughput

0.621

High

703517

MK01
Mitogen-activated protein kinase 1

1

11

High-throughput

0.618

High

842905

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

15

High-throughput

0.618

High

842948

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

19

High-throughput

0.618

High

937510

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

20

Small-scale

0.618

High

140197

SDCB1
Syntenin-1

2

13

High-throughput

0.606

High

192364

GSC2
Homeobox protein goosecoid-2

2

12

High-throughput

0.606

High

341752

K2C75
Keratin, type II cytoskeletal 75

2

4

High-throughput

0.606

High

505701

ZN688
Zinc finger protein 688

2

12

High-throughput

0.606

High

680827

PSA1
Proteasome subunit alpha type-1

2

3

High-throughput

0.606

High

716415

PRDX5
Peroxiredoxin-5, mitochondrial

2

1

High-throughput

0.606

High

718875

CCND3
G1/S-specific cyclin-D3

2

12

High-throughput

0.606

High

937472

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

19

High-throughput

0.606

High

937474

GLYR1
Cytokine-like nuclear factor N-PAC

2

4

High-throughput

0.606

High

937478

ZN774
Zinc finger protein 774

2

3

High-throughput

0.606

High

937481

ZN620
Zinc finger protein 620

2

3

High-throughput

0.606

High

937485

LNX1
E3 ubiquitin-protein ligase LNX

2

17

High-throughput

0.606

High

937489

NR4A3
Nuclear receptor subfamily 4 group A member 3

2

20

High-throughput

0.606

High

937495

ZN396
Zinc finger protein 396

2

4

High-throughput

0.606

High

937502

NIF3L
NIF3-like protein 1

2

2

High-throughput

0.606

High

937506

PICK1
PRKCA-binding protein

2

3

High-throughput

0.606

High

937509

THAP1
THAP domain-containing protein 1

2

1

High-throughput

0.606

High

937516

MTF2
Metal-response element-binding transcription factor 2

2

2

High-throughput

0.606

High

2891

A0A0C4DGF1
Zinc finger and BTB domain containing 32

1

2

High-throughput

0.594

High

937463

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

0

High-throughput

0.580

High

937487

DYT2B
Dynein light chain Tctex-type protein 2B

2

0

High-throughput

0.580

High

937488

P66B
Transcriptional repressor p66-beta

2

0

High-throughput

0.580

High

937491

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

937493

PRIPO
DNA-directed primase/polymerase protein

2

0

High-throughput

0.580

High

937499

VGLL1
Transcription cofactor vestigial-like protein 1

2

0

High-throughput

0.580

High

937512

CGBP1
CGG triplet repeat-binding protein 1

2

0

High-throughput

0.580

High

937468

CTBP1
C-terminal-binding protein 1

1

9

High-throughput

0.573

High

143819

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

3

High-throughput

0.553

High

937480

RUFY4
RUN and FYVE domain-containing protein 4

2

5

High-throughput

0.553

High

937503

GORS2
Golgi reassembly-stacking protein 2

2

1

High-throughput

0.553

High

937508

F86C1
Putative protein FAM86C1P

2

1

High-throughput

0.553

High

937504

TBC17
TBC1 domain family member 17

1

2

High-throughput

0.541

High

937460

BTG1
Protein BTG1

1

0

High-throughput

0.536

High

937462

H11
Histone H1.1

1

6

High-throughput

0.536

High

937507

RBM12
RNA-binding protein 12

1

7

High-throughput

0.536

High

98528

F1D8N6
Nuclear receptor subfamily 4 group A member 2

1

20

High-throughput

0.515

High

937477

Q6FHY5
MEOX2 protein

1

8

High-throughput

0.515

High

631811

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.513

High

937490

PTER
N-acetyltaurine hydrolase

1

0

High-throughput

0.513

High

937492

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.513

High

421797

A4
Amyloid-beta precursor protein

1

10

High-throughput

0.501

High

893776

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

937459

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

2

High-throughput

0.481

High

937467

NMI
N-myc-interactor

1

1

High-throughput

0.481

High

937496

QKI
KH domain-containing RNA-binding protein QKI

1

1

High-throughput

0.481

High

520541

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.479

High

713980

PML
Protein PML

1

11

Small-scale

0.479

High

842702

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

18

High-throughput

0.479

High

932456

KAD2
Adenylate kinase 2, mitochondrial

1

7

High-throughput

0.479

High

937471

CDC37
Hsp90 co-chaperone Cdc37

1

6

High-throughput

0.479

High

937494

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

937497

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.460

High

937466

SEPR
Prolyl endopeptidase FAP

1

2

High-throughput

0.445

High

937470

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.426

High

479182

HBAT
Hemoglobin subunit theta-1

1

1

High-throughput

0.407

High

937479

CA094
Uncharacterized protein C1orf94

3

0

High-throughput

0.350

High

62716

CFA90
Cilia- and flagella-associated protein 90

2

0

High-throughput

0.316

High

71507

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

605447

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

937473

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

937475

MSS51
Putative protein MSS51 homolog, mitochondrial

2

0

High-throughput

0.316

High

937482

F228A
Protein FAM228A

2

0

High-throughput

0.316

High

937484

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.316

High

937501

UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2

2

0

High-throughput

0.316

High

937486

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.279

Low

937498

RARR2
Retinoic acid receptor responder protein 2

1

0

High-throughput

0.279

Low

937511

MTFP1
Mitochondrial fission process protein 1

1

0

High-throughput

0.269

Low

937458

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

937483

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025