HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: FBXW4 (P57775)
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
Gene: FBXW4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 23658844
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 412
+	Hs
		843089 TCPQ_HUMAN (1-548): 0: 616: 100.00		FBW1B_HUMAN (34-411): 3.49e-81: 260: 16.03
+	Hs
		842812 TCPQ_HUMAN (1-548): 0: 616: 100.00		WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61
+	Hs
		885053 TCPH_HUMAN (9-538): 0: 564: 26.39		FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22
+	Hs
		826588 TCPG_HUMAN (10-547): 0: 558: 28.21		FBXW4_HUMAN (21-412): 3.66e-83: 262: 98.22
+	Hs
		792942 TCPG_HUMAN (10-547): 0: 558: 28.21		LIS1_HUMAN (7-322): 9.15e-67: 219: 13.20
+	Hs
		903467 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61
+	Hs
		826601 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61
+	Hs
		1202777 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80
+	Hs
		826748 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR5B_HUMAN (33-319): 2.7e-61: 203: 12.80
+	Hs
		842958 TCPQ_HUMAN (1-548): 0: 616: 100.00		POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27
+	Hs
		842938 TCPQ_HUMAN (1-548): 0: 616: 100.00		WDR86_HUMAN (153-399): 2.12e-22: 99.5: 17.74
+	Hs
		1240450 TCPH_HUMAN (9-538): 0: 564: 26.39		POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27
+	Hs
		826772 TCPG_HUMAN (10-547): 0: 558: 28.21		POC1A_HUMAN (22-227): 1.35e-37: 142: 11.27
+	Hs
		1306654 TCPH_HUMAN (9-538): 0: 564: 26.39		KTNB1_HUMAN (100-275): 1.19e-32: 132: 15.47
+	Hs
		842990 TCPQ_HUMAN (1-548): 0: 616: 100.00		SNR40_HUMAN (322-411): 5.98e-14: 74.5: 14.29
+	Hs
		843102 TCPQ_HUMAN (1-548): 0: 616: 100.00		FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83
+	Hs
		1198554 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR86_HUMAN (153-399): 2.12e-22: 99.5: 17.74
+	Hs
		826743 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR86_HUMAN (153-399): 2.12e-22: 99.5: 17.74
+	Hs
		1306704 TCPH_HUMAN (9-538): 0: 564: 26.39		NLE1_HUMAN (328-411): 2.65e-17: 85.6: 11.91
+	Hs
		1306744 TCPH_HUMAN (9-538): 0: 564: 26.39		FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83