HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	26496610, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 309
+	Hs
		842815 TCPQ_HUMAN (1-548): 0: 616: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		842804 TCPQ_HUMAN (1-548): 0: 616: 100.00		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Mm
		792269 TCPQ_MOUSE (1-548): 0: 617: 96.90		PP1A_MOUSE (5-296): 0: 504: 46.84
+	Hs
		930969 TCPH_HUMAN (9-538): 0: 564: 26.39		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915267 TCPH_HUMAN (9-538): 0: 564: 26.39		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		826610 TCPG_HUMAN (10-547): 0: 558: 28.21		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		826603 TCPG_HUMAN (10-547): 0: 558: 28.21		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		890997 TCPH_HUMAN (9-538): 0: 564: 26.39		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		826591 TCPG_HUMAN (10-547): 0: 558: 28.21		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		821161 TCPE_HUMAN (2-524): 0: 535: 29.62		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		821154 TCPE_HUMAN (2-524): 0: 535: 29.62		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		843150 TCPD_HUMAN (19-525): 0: 530: 28.24		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		843141 TCPD_HUMAN (19-525): 0: 530: 28.24		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		573203 TCPA_HUMAN (21-541): 0: 528: 29.89		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Sc
		618781 TCPH_YEAST (7-542): 0: 534: 28.34		PP2A1_YEAST (10-309): 0: 517: 76.00
+	Sc
		618845 TCPH_YEAST (7-542): 0: 534: 28.34		PP2A2_YEAST (10-309): 0: 514: 76.67
+	Hs
		821143 TCPE_HUMAN (2-524): 0: 535: 29.62		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		843130 TCPD_HUMAN (19-525): 0: 530: 28.24		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Hs
		573192 TCPA_HUMAN (21-541): 0: 528: 29.89		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Sc
		594334 TCPH_YEAST (7-542): 0: 534: 28.34		PP11_YEAST (11-309): 1.47e-137: 393: 57.71