HitPredict

Interactor 1: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Interactor 2: VP13C (Q709C8)
Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C)
Gene: VPS13C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 29568061, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005770 - late endosome GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Hs			1 3753
+	Hs
		1070263 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		845018 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		918895 RAB1A_HUMAN (2-201): 3.43e-79: 236: 32.68		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		1173713 RAB1B_HUMAN (2-201): 1.7e-77: 232: 32.02		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		914157 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		1070353 RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		845185 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		845683 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		914296 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Dm
		51968 RAB7_DROME (1-180): 6.29e-65: 200: 51.93		VPS13_DROME (1-1458): 0: 976: 28.59
+	Dm
		1368188 Q9VIW6_DROME (4-192): 1.8e-65: 203: 51.81		VP13D_DROME (2629-3635): 5.06e-109: 395: 17.83
+	Hs
		845149 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		ATG2B_HUMAN (4-362): 1.94e-59: 231: 16.75
+	Hs
		844958 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		ATG2A_HUMAN (4-362): 4.38e-52: 206: 14.71
+	Hs
		845512 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		ATG2A_HUMAN (4-362): 4.38e-52: 206: 14.71
+	Hs
		47676 RAB1A_HUMAN (2-201): 3.43e-79: 236: 32.68		A0AUL9_HUMAN (4-362): 8.15e-56: 206: 14.71
+	Hs
		844983 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		VP13D_HUMAN (1041-2048): 1.94e-43: 179: 14.23
+	Hs
		845530 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		VP13D_HUMAN (1041-2048): 1.94e-43: 179: 14.23
+	Hs
		845036 RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24		VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22
+	Hs
		845574 RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00		VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22
+	Hs
		914175 RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38		VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22