HitPredict

Interactor 1: GRK6 (P43250)
G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)
Gene: GRK6

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 576 Hs			1 365
+	Hs
		846730 GRK6_HUMAN (1-576): 0: 579: 100.00		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		728495 AKT1_HUMAN (82-497): 1.46e-144: 427: 31.10		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		846790 GRK6_HUMAN (1-576): 0: 579: 100.00		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		650594 KAPCG_HUMAN (144-500): 1.72e-143: 420: 26.89		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Mm
		1221330 ARBK1_MOUSE (2-533): 7.6e-146: 438: 36.77		PPP5_MOUSE (9-249): 1.45e-39: 148: 14.69
+	Rn
		916731 AKT3_RAT (75-496): 8.35e-144: 425: 30.73		PPP5_RAT (4-249): 1.94e-39: 148: 14.80
+	Hs
		650535 KAPCG_HUMAN (144-500): 1.72e-143: 420: 26.89		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		650579 KAPCG_HUMAN (144-500): 1.72e-143: 420: 26.89		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		1458662 KS6B2_HUMAN (186-485): 2.74e-57: 201: 39.09		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		603253 KPCA_HUMAN (176-496): 1.88e-58: 208: 38.08		SPAG1_HUMAN (2-339): 1.14e-24: 107: 12.39