HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1647 Hs			1 1834
+	Hs
		1059725 CHD4_HUMAN (482-1630): 0: 722: 23.79		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		151429 CHD1_HUMAN (355-1641): 0: 713: 23.83		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1222585 CHD8_HUMAN (13-1523): 0: 711: 21.11		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1109050 CHD9_HUMAN (67-1534): 0: 702: 20.82		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1222593 HELLS_HUMAN (683-1234): 1.22e-106: 362: 36.56		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		847041 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		847124 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		CABIN_HUMAN (880-1364): 9.59e-09: 63.1: 13.91
+	Hs
		801032 SMCA2_HUMAN (1-1647): 0: 980: 71.69		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		846837 SMCA2_HUMAN (1-1647): 0: 980: 71.69		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		801147 CHD4_HUMAN (482-1630): 0: 722: 23.79		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		801108 CHD3_HUMAN (300-1646): 0: 711: 20.80		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		801399 CHD8_HUMAN (13-1523): 0: 711: 21.11		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		1056830 CHD4_HUMAN (482-1630): 0: 722: 23.79		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		965161 CHD8_HUMAN (13-1523): 0: 711: 21.11		ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18
+	Dm
		332845 CHDM_DROME (555-1640): 0: 704: 24.13		Q9VGW4_DROME (894-1788): 1.73e-11: 72: 10.08
+	Hs
		1018618 CHD3_HUMAN (300-1646): 0: 711: 20.80		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		801437 CHD7_HUMAN (104-638): 1.93e-11: 71.7: 8.99		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79