Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Interactor 2: PALB2 (Q86YC2)
Partner and localizer of BRCA2
Gene: PALB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 22293751, 26833090, 21466675, 28765325, 24835992, 20871615, 16793542, 19369211, 19609323, 22193777, 26649820, 25016020, 26990772, 24141787, 22331464, 28240985, 28319063, 28398198, 33961781, 34591612 and 9 others

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Identification Methods affinity chromatography technology, pull down, unspecified method, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, bimolecular fluorescence complementation, fluorescence technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0001833 - inner cell mass cell proliferation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032991 - protein-containing complex
and 1 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 3418
Hs

1 1186
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024