HitPredict

Interactor 1: RUXF (Q24297)
Small nuclear ribonucleoprotein F (snRNP-F) (Membrane-associated protein Deb-B) (Sm protein F) (Sm-F) (SmF)
Gene: SmF

Interactor 2: RU2A (Q9V4Q8)
Probable U2 small nuclear ribonucleoprotein A' (U2 snRNP A')
Gene: U2A

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_9~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0030532 - small nuclear ribonucleoprotein complex GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 88 Dm			1 265
+	Sp
		237621 RUXF_SCHPO (3-76): 5.58e-30: 103: 67.57		RU2A_SCHPO (2-239): 8.29e-52: 170: 37.92
+	Dm
		1465921 Q9VKW8_DROME (9-82): 1.17e-32: 112: 29.33		RU2A_DROME (1-265): 3.47e-47: 159: 100.00
+	Sp
		1462903 SMD3_SCHPO (10-78): 3.78e-25: 91.5: 21.74		RU2A_SCHPO (2-239): 8.29e-52: 170: 37.92
+	Dm
		1465946 Q9W2P5_DROME (11-81): 2.46e-27: 96.5: 43.66		RU2A_DROME (1-265): 3.47e-47: 159: 100.00
+	Sc
		933152 RUXF_YEAST (1-79): 2.72e-28: 98.8: 53.75		RU2A_YEAST (2-235): 2.17e-45: 154: 23.17
+	Hs
		485600 RUXF_HUMAN (5-77): 4.98e-32: 108: 82.19		RU2A_HUMAN (1-244): 1.03e-39: 139: 52.46
+	Dm
		232179 SMD3_DROME (9-78): 3.62e-22: 85.3: 22.86		RU2A_DROME (1-265): 3.47e-47: 159: 100.00
+	Sc
		847841 SMD3_YEAST (9-78): 6.94e-24: 88.4: 24.29		RU2A_YEAST (2-235): 2.17e-45: 154: 23.17
+	Hs
		1293329 LSM2_HUMAN (11-88): 1.3e-24: 90: 28.40		DAA11_HUMAN (1-249): 1.73e-40: 147: 20.70
+	Sc
		818067 LSM4_YEAST (9-83): 4.32e-20: 81.1: 26.74		RU2A_YEAST (2-235): 2.17e-45: 154: 23.17
+	Dm
		1466495 Q9VKW8_DROME (9-82): 1.17e-32: 112: 29.33		AN32A_DROME (20-154): 1.77e-31: 118: 29.63
+	Hs
		485767 LSM2_HUMAN (11-88): 1.3e-24: 90: 28.40		RU2A_HUMAN (1-244): 1.03e-39: 139: 52.46
+	Sc
		1054946 LSM6_YEAST (11-78): 1.26e-18: 74.6: 34.72		RU2A_YEAST (2-235): 2.17e-45: 154: 23.17
+	Hs
		485604 SMD3_HUMAN (9-78): 8.28e-24: 88.8: 22.86		RU2A_HUMAN (1-244): 1.03e-39: 139: 52.46