HitPredict

Interactor 1: MAGA4 (P43358)
Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)
Gene: MAGEA4

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	32296183, 25416956, 26186194, 28514442, 33961781, 31515488, unassigned3799
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 1084
+	Hs
		1169436 Q1RN33_HUMAN (1-305): 1.21e-156: 442: 99.67		AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00
+	Hs
		848336 MAGA4_HUMAN (1-305): 1.82e-156: 441: 100.00		AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28
+	Hs
		59910 MAGA4_HUMAN (1-305): 1.82e-156: 441: 100.00		A2BDD9_HUMAN (410-1084): 8.22e-39: 157: 99.70
+	Hs
		1169443 Q1RN33_HUMAN (1-305): 1.21e-156: 442: 99.67		AMOL2_HUMAN (296-902): 1.23e-28: 125: 40.92
+	Hs
		848359 MAGA4_HUMAN (1-305): 1.82e-156: 441: 100.00		AMOL2_HUMAN (296-902): 1.23e-28: 125: 40.92
+	Hs
		191881 MAGB3_HUMAN (1-317): 2.91e-141: 404: 41.25		MYH7_HUMAN (349-838): 2.02e-18: 93.8: 10.02
+	Hs
		191882 MAGB3_HUMAN (1-317): 2.91e-141: 404: 41.25		MYH6_HUMAN (251-882): 4.42e-17: 89.2: 9.75
+	Hs
		191890 MAGB3_HUMAN (1-317): 2.91e-141: 404: 41.25		MYH2_HUMAN (511-905): 1.48e-10: 68.1: 10.47
+	Hs
		848383 MAGA6_HUMAN (1-315): 7.21e-143: 407: 68.25		DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85
+	Hs
		556872 MAGB5_HUMAN (75-315): 4.2e-111: 325: 42.21		MYH1_HUMAN (144-882): 1.6e-15: 84.2: 8.45
+	Hs
		772977 NECD_HUMAN (27-313): 4.91e-93: 280: 27.95		MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38
+	Mm
		148293 NECD_MOUSE (27-311): 2.04e-98: 294: 27.89		DCTN1_MOUSE (510-863): 1.39e-09: 64.5: 14.85
+	Hs
		773256 NECD_HUMAN (27-313): 4.91e-93: 280: 27.95		MYH10_HUMAN (389-818): 6.65e-13: 75.8: 18.35
+	Hs
		254460 MAGC1_HUMAN (82-316): 1.43e-79: 263: 46.38		ROCK2_HUMAN (363-853): 4.77e-18: 92.2: 12.75