Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 26972000
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Ank_4~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0106310 - protein serine kinase activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 712
Hs

1 832
+ Hs
+ At
+ Hs
+ At
+ Mm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024