Interactor 1: IRAK1 (P51617)
Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)
Gene: IRAK1

Interactor 2: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 16306936
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008063 - Toll signaling pathway
GO:0010008 - endosome membrane
and 5 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 712
Hs

1 568
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024