HitPredict

Interactor 1: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 17353931, 26186194, 28514442, 28292943, 33961781, 35271311, 19615732
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PCI, MitMem_reg~PCI
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 324
Hs

1 389
+ Dm
+ Mm
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp
+ At
+ Hs
+ Dm
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024