HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: RNF26 (Q9BY78)
E3 ubiquitin-protein ligase RNF26 (EC 2.3.2.27) (RING finger protein 26)
Gene: RNF26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.781

Property	Details
Experiments	19549727, 32614325
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 433
+	Hs
		1316184 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		RNF26_HUMAN (1-433): 0: 684: 100.00
+	Hs
		849400 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		BIRC7_HUMAN (292-433): 1.92e-40: 147: 24.66
+	Hs
		849321 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		BIRC3_HUMAN (321-433): 8.68e-28: 117: 23.01
+	Hs
		919721 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		BIRC3_HUMAN (321-433): 8.68e-28: 117: 23.01
+	Hs
		282379 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		NEUL1_HUMAN (307-432): 4.61e-26: 112: 25.40
+	Hs
		849322 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		BIRC2_HUMAN (321-433): 3.8e-25: 109: 23.01
+	Hs
		919722 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		BIRC2_HUMAN (321-433): 3.8e-25: 109: 23.01
+	Dm
		639392 UBCD1_DROME (1-147): 1.87e-81: 238: 89.12		DIAP1_DROME (313-433): 2.93e-23: 103: 20.31
+	Hs
		1298970 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		BIRC8_HUMAN (335-433): 2.84e-23: 99.4: 26.26
+	Hs
		957802 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		XIAP_HUMAN (335-433): 3.47e-21: 97.5: 20.20
+	Hs
		849413 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		BIRC8_HUMAN (335-433): 2.84e-23: 99.4: 26.26
+	Hs
		849308 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		XIAP_HUMAN (335-433): 3.47e-21: 97.5: 20.20
+	Hs
		919707 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		XIAP_HUMAN (335-433): 3.47e-21: 97.5: 20.20
+	Hs
		1264347 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		MYLIP_HUMAN (357-433): 2.06e-18: 89: 22.08
+	Hs
		849386 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MYLIP_HUMAN (357-433): 2.06e-18: 89: 22.08
+	Hs
		230183 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		MGRN1_HUMAN (352-431): 2.67e-14: 76.7: 28.75
+	Hs
		230126 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		MGRN1_HUMAN (352-431): 2.67e-14: 76.7: 28.75
+	Hs
		230132 UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12		MGRN1_HUMAN (352-431): 2.67e-14: 76.7: 28.75
+	Hs
		849387 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		RFFL_HUMAN (376-432): 1.79e-13: 73.2: 28.07
+	At
		715118 UBC8_ARATH (1-147): 3.61e-82: 239: 76.19		LUL3_ARATH (377-431): 7.7e-13: 71.3: 40.00