HitPredict

Interactor 1: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Interactor 2: UBE2S (Q16763)
Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)
Gene: UBE2S

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20622874
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 222
+	Hs
		906728 USP9X_HUMAN (289-795): 1.16e-86: 305: 14.26		UB2D1_HUMAN (11-157): 3.81e-83: 245: 35.37
+	Hs
		1162686 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		UBE2S_HUMAN (1-222): 3.29e-86: 256: 100.00
+	Hs
		957151 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		UB2D3_HUMAN (11-157): 3.05e-82: 243: 35.37
+	Hs
		288423 UBP2_HUMAN (281-660): 3.14e-79: 269: 14.18		UBE2S_HUMAN (1-222): 3.29e-86: 256: 100.00
+	Hs
		1371585 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		UB2E3_HUMAN (2-157): 1.06e-75: 229: 32.05
+	Hs
		909362 UBP7_HUMAN (247-777): 1e-83: 292: 13.54		UB2E1_HUMAN (1-157): 4.15e-76: 229: 31.85
+	Hs
		1162720 UBP21_HUMAN (319-594): 1.47e-25: 114: 19.64		UBE2S_HUMAN (1-222): 3.29e-86: 256: 100.00
+	Hs
		906820 UBP21_HUMAN (319-594): 1.47e-25: 114: 19.64		UB2D1_HUMAN (11-157): 3.81e-83: 245: 35.37
+	Hs
		884369 UBP33_HUMAN (174-455): 1.14e-24: 113: 22.18		UBE2A_HUMAN (8-154): 4.95e-72: 217: 34.01