Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: NEK9 (Q8TD19)
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)
Gene: NEK9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.700

The method score is based on:

Property Details
Experiments 21642957
Identification Methods pull down, anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000278 - mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005813 - centrosome
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 603
Hs

1 979
+ Mm
+ Hs
+ Hs
+ Gm
+ At
+ At
+ At
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+ At
+ At
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+ At
+ Hs
+ At
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+ Hs

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Last updated: 15 Jul 2024