HitPredict

Interactor 1: ARFP2 (P53365)
Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (POR1)
Gene: ARFIP2

Interactor 2: ARF3 (P61204)
ADP-ribosylation factor 3
Gene: ARF3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	9038142, 35844135, 9312003
Identification Methods	pull down, proximity labelling technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Arf~Arfaptin
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 341 Hs			1 181
+	Hs
		862150 ARFP2_HUMAN (1-341): 1.29e-149: 426: 100.00		ARF6_HUMAN (5-179): 2.68e-73: 219: 69.14
+	Hs
		862153 ARFP2_HUMAN (1-341): 1.29e-149: 426: 100.00		ARF1_HUMAN (1-181): 1.98e-68: 207: 96.13
+	Hs
		862154 ARFP2_HUMAN (1-341): 1.29e-149: 426: 100.00		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		862215 ARFP1_HUMAN (8-341): 1.68e-143: 412: 54.62		ARF6_HUMAN (5-179): 2.68e-73: 219: 69.14
+	Hs
		574630 ARFP2_HUMAN (1-341): 1.29e-149: 426: 100.00		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Hs
		862213 ARFP1_HUMAN (8-341): 1.68e-143: 412: 54.62		ARF3_HUMAN (1-181): 2.09e-68: 207: 100.00
+	Hs
		862219 ARFP1_HUMAN (8-341): 1.68e-143: 412: 54.62		ARF1_HUMAN (1-181): 1.98e-68: 207: 96.13
+	Hs
		862220 ARFP1_HUMAN (8-341): 1.68e-143: 412: 54.62		ARF5_HUMAN (1-180): 1.91e-68: 207: 78.89
+	Hs
		574631 ARFP1_HUMAN (8-341): 1.68e-143: 412: 54.62		ARF4_HUMAN (1-180): 2.97e-65: 199: 78.89
+	Dm
		778408 Q9VGQ8_DROME (74-340): 2.78e-102: 306: 55.81		ARF6_DROME (5-176): 1e-71: 216: 69.77