Interactor 1: ARFP2 (P53365)
Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (POR1)
Gene: ARFIP2
Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11478794, 29997244, 26264872, 8670882, 11346801, 21988832, unassigned1913, 9312003 |
| Identification Methods | two hybrid, fluorescent resonance energy transfer, affinity chromatography technology, pull down, x-ray crystallography, split luciferase complementation, protein complementation assay, mammalian protein protein interaction trap, beta galactosidase complementation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arfaptin~Ras |
| Common GO terms | GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005938 - cell cortex and 4 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
