HitPredict

Interactor 1: SSU72 (P53538)
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) (Suppressor of SUA7 protein 2)
Gene: SSU72

Interactor 2: CFT2 (Q12102)
Cleavage factor two protein 2 (105 kDa protein associated with polyadenylation factor I)
Gene: CFT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	12853609, 16554755, 37968396, 12819204, 12704082, 12453421, 22235117
Identification Methods	affinity chromatography technology, pull down, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 206 Sc			1 859
+	Hs
		1342422 SSU72_HUMAN (1-206): 1.79e-105: 303: 43.69		CPSF2_HUMAN (14-859): 0: 765: 19.40
+	Hs
		1342424 SSU72_HUMAN (1-206): 1.79e-105: 303: 43.69		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99
+	Sc
		862605 SSU72_YEAST (1-206): 3.1e-118: 335: 100.00		YSH1_YEAST (2-430): 2.45e-134: 421: 15.86
+	Sp
		142953 SSU72_SCHPO (7-206): 4.79e-110: 314: 52.00		YSH1_SCHPO (10-444): 8.67e-135: 421: 15.89