HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	34079125, 10359664
Identification Methods	proximity labelling technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0006915 - apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 332
+	Hs
		625147 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Hs
		625528 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71
+	Hs
		669983 CDK16_HUMAN (1-297): 6.03e-124: 364: 51.68		MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00
+	Mm
		581220 CDK5_MOUSE (1-293): 2.32e-134: 383: 56.12		NFH_MOUSE (2-327): 6.57e-11: 65.6: 15.90
+	Rn
		974742 CDK5_RAT (1-293): 9.73e-134: 382: 56.12		SYNJ1_RAT (2-330): 4.78e-09: 59.8: 10.09
+	Dm
		820723 CDK5_DROME (1-289): 4.62e-131: 375: 54.48		CPN_DROME (34-331): 7.5e-09: 59: 13.29