HitPredict

Interactor 1: HM01 (P53547)
Homeobox protein ceh-1
Gene: ceh-1

Interactor 2: FKH6 (Q10924)
Forkhead transcription factor fkh-6
Gene: fkh-6

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0030154 - cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Ce			1 323
+	Ce
		712507 LIN39_CAEEL (2-84): 1.85e-30: 111: 40.96		FKH6_CAEEL (1-323): 5.58e-134: 385: 100.00
+	Mm
		192278 ALX4_MOUSE (2-132): 4.2e-34: 123: 25.95		FOXH1_MOUSE (6-302): 6.37e-62: 204: 22.85
+	Hs
		595599 HXA5_HUMAN (2-70): 1.47e-35: 124: 47.83		FOXO1_HUMAN (23-312): 4.07e-52: 183: 22.41
+	Dm
		685379 UBX_DROME (2-62): 3.11e-33: 121: 45.90		FD5_DROME (11-224): 4.11e-56: 184: 28.95
+	Hs
		620242 PAX3_HUMAN (2-129): 8.25e-33: 121: 31.30		FOXO1_HUMAN (23-312): 4.07e-52: 183: 22.41
+	Dm
		950049 UBX_DROME (2-62): 3.11e-33: 121: 45.90		Q9V481_DROME (6-228): 1.03e-47: 170: 27.78
+	Mm
		192285 ALX4_MOUSE (2-132): 4.2e-34: 123: 25.95		FOXA1_MOUSE (14-300): 5.06e-47: 166: 22.64
+	Hs
		877884 ALX4_HUMAN (2-132): 5.62e-34: 123: 25.95		FOXA1_HUMAN (14-300): 1.11e-46: 165: 24.41
+	Hs
		878008 ALX4_HUMAN (2-132): 5.62e-34: 123: 25.95		FOXA3_HUMAN (4-143): 3.35e-47: 164: 40.85
+	Hs
		595649 HXA5_HUMAN (2-70): 1.47e-35: 124: 47.83		FOXA2_HUMAN (21-123): 1.33e-45: 162: 47.57
+	Hs
		1305647 PITX2_HUMAN (2-129): 4.7e-29: 108: 27.91		FOXC2_HUMAN (5-234): 1.21e-50: 176: 30.93
+	Hs
		620149 PAX7_HUMAN (2-117): 8e-31: 116: 26.72		FOXC1_HUMAN (5-192): 1.39e-46: 167: 34.04
+	Ce
		106263 VAB3_CAEEL (1-130): 9.02e-32: 118: 25.95		FKH02_CAEEL (15-193): 4.02e-48: 164: 32.43
+	Hs
		126476 ALX4_HUMAN (2-132): 5.62e-34: 123: 25.95		FOXE1_HUMAN (21-116): 9.06e-45: 158: 52.08
+	Hs
		126430 PAX3_HUMAN (2-129): 8.25e-33: 121: 31.30		FOXE1_HUMAN (21-116): 9.06e-45: 158: 52.08
+	Dm
		447328 SCR_DROME (2-66): 2.73e-33: 121: 46.15		SLP2_DROME (12-139): 7.09e-44: 157: 43.75
+	Dm
		685392 UBX_DROME (2-62): 3.11e-33: 121: 45.90		SLP2_DROME (12-139): 7.09e-44: 157: 43.75
+	Hs
		1021150 PITX2_HUMAN (2-129): 4.7e-29: 108: 27.91		FOXC1_HUMAN (5-192): 1.39e-46: 167: 34.04
+	Hs
		686587 OTX2_HUMAN (2-119): 7.25e-30: 110: 26.92		FOXA2_HUMAN (21-123): 1.33e-45: 162: 47.57
+	Hs
		270768 MSX2_HUMAN (2-115): 3.04e-14: 68.9: 43.48		FOXH1_HUMAN (4-300): 3.96e-51: 174: 20.60