HitPredict

Interactor 1: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 486
+	Hs
		872430 EPHA5_HUMAN (1-1037): 0: 1374: 100.00		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		872730 EPHA4_HUMAN (33-1035): 0: 1223: 62.04		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		1072628 EPHA7_HUMAN (37-1035): 0: 1222: 62.69		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		665683 EPHB2_HUMAN (60-1034): 0: 1209: 56.80		PACN2_HUMAN (1-486): 1.94e-100: 311: 100.00
+	Hs
		872636 EPHA4_HUMAN (33-1035): 0: 1223: 62.04		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		1001576 EPHA7_HUMAN (37-1035): 0: 1222: 62.69		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		665588 EPHB2_HUMAN (60-1034): 0: 1209: 56.80		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		435625 IGF1R_HUMAN (294-1017): 7.97e-145: 469: 23.00		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		674424 UFO_HUMAN (290-1017): 4.06e-147: 463: 21.89		SRC8_HUMAN (47-484): 5.84e-38: 147: 11.40
+	Hs
		297957 FGFR3_HUMAN (404-988): 2.12e-147: 461: 21.80		FCSD2_HUMAN (38-485): 6.87e-12: 69.8: 13.81
+	Hs
		433776 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		CIP4_HUMAN (12-465): 9.47e-47: 173: 15.03
+	Hs
		433725 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		FCHO2_HUMAN (14-444): 1.2e-45: 172: 14.06
+	Hs
		433957 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Mm
		639446 LYN_MOUSE (659-933): 3.02e-65: 231: 43.68		SRC8_MOUSE (47-484): 1.33e-40: 154: 12.17
+	Hs
		433732 LYN_HUMAN (659-933): 1.73e-65: 231: 43.68		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04